41 results
The proposal is organized around five interrelated themes:1. Unravel the interplay between genetic and environmental influences on substance use by using extended twin-family designs.2. Disentangle genes and pathways involved in substance use with…
The aim of this study is to determine whether dopamine modifies the metabolic activity of BAT. Furthermore, we want to investigate the relation between the metabolic activity of BAT with energy expenditure and glucose tolerance in these individuals.
The overall objective of this study is to increase the uptake and maintenance of healthy behaviors among adults from non-Western immigrant populations who are identified as having a high risk of cardiometabolic disease after completing a health…
Primary objective: To assess the influence of the addition of rinsing with a 0.05% chlorhexidine-containing solution to usual daily oral hygiene care on the incidence of pneumonia in physically-impaired care home residents with dysphagia.Secondary…
Primairy objective: To investigate whether the sympathetic stimulation of BAT, as assessed with a MIBG SPECT-CT scan, differs between young and elderly subjects.Secondary Objectives: 1) To investigate whether the slope of the correlation between…
We expect to determine the prevalence of IPV at the ED of University Nijmegen Medical Centre and to find specific characteristics of victims of IPV, like the complaints they present themselves with and their educational and geographic background and…
The main objective of this study is to evaluate the effectiveness of a newly developed interdisciplinary tailor-made social fitness programme on the participation in meaningful social activities of community-dwelling older people with dementia and…
The aim of the study is to examine the well-being of the children involved in fatal partner violence, in terms of post traumatic stress, comorbid psychopathology, mourning, daily functioning and quality of life. In addition, the aim is to…
To gather information about the development of 1. foot structure, 2. foot complaints, 3. plantar pressure distribution and 4. centre of pressure progression in feet over time in ageing women. 5. To determine the fit of shoes based on currently used…
Primary Objective: The primary objective of this study is to understand to which degree the language system of pre-pubertal children is still plastic compared to adults and which brain areas are recruited by these groups when learning an artificial…
Investigate how physical fitness and activity evolve over time in paediatric burn patients, also in relation to function.
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
Our aim is to improve patient and doctor satisfaction and quality of the discussion about potential treatment restrictions by introducing a digital information and conversation aid for patients and training for doctors. Moreover, we aim to provide…
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
The PowerMe study will analyse fatigue characteristics and severity in children and adolescents with mitochondrial myopathy and their families. Then a blended personalized cognitive behaviour therapy program for fatigue will be designed and tested,…
This study is designed to test the hypothesis that in-hospital dance courses are a feasible non-pharmacological intervention for improving quality of life in community-dwelling people with dementia. Current study is a pilot study, meaning it's…
The overall aim of this study is to identify developmental deficits in children with Rolandic epilepsy. If developmental deficits are observed, we hope to determine timing, persistence, and prognostic factors for developmental deficits and improve…
The primary objectives of this study are:1. To assess the amount of physical activity of acutely hospitalized elderly *70 years during hospitalization and to create reference values regarding the amount of time patients are standing and walking per…
The aim of this study is to test the feasibility of this algorithm as an intervention to carry out deprescribing a targeted medication group, proton pumpinhibitors (PPI*s) and statins, among nursing home residents.
Our primary aims are 1) to test with observational and electrophysiological techniques whether intranasal oxytocin administration to mothers of young infants increases their defensive reactivity and protective approach responses in mildly…