20 results
The main objective of the present protocol is to investigate to what extent oxytocin modulates specific aspects of interpersonal approach, mimicry, and communication in healthy volunteers with varying degrees of social anxiety.Results from this…
This study will investigate the counter impulse hypothesis. According to the counter-impulse hypothesis, avoidance motivation counters aggressive impulses. Consequently, this regulatory impact should be especially effective when people*s aggressive…
Our primary aims are 1) to test with observational and electrophysiological techniques whether intranasal oxytocin administration to mothers of young infants increases their defensive reactivity and protective approach responses in mildly…
The goal is to study whther the daily intake of consumer foods enriched with fish oil or seaweed extracts influences mood, mental capacity or antioxidant status in healthy subjects.
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
In this study neural responses to infant crying will be measured with fMRI. In addition, the neural base of emotion understanding will be examined with fMRI. Participants will look at pictures of adults and infant and they have to infer the mental…
This proposal centers on hormone-behavior dynamics in paternal caregiving, with the goal of gaining a better understanding of the development of human paternal caregiving. There is limited information on the hormonal basis of caregiving patterns in…
This proposal centers on hormone-behavior dynamics in paternal caregiving, with the goal of gaining a better understanding of the development of human paternal caregiving. There is limited information on the hormonal basis of caregiving patterns in…
Determine the effectiveness of Triple P, level 3, in Dutch PCH.
To characterize the multiple-dose pharmacokinetics of varenicline in adolescent maleand female smoking subjects
Primary research questions: 1. Is there a difference in effectiveness of clozapine treatment compared to olanzapine treatment in the reduction of substance use disorders of patients with schizophrenia and related psychotic disorders? 2. What is the…
Primary objective- To assess the effects of Org 25935 on heavy drinking in subjects with alcohol dependence.Secondary objectives- assess the effects of Org 25935 on the amount of drinking- To assess the effects of Org 25935 on the first relapse to…
The main objective of the present protocol is to investigate to what extent oxytocin modulates specific aspects of approach behavior and action control in healthy volunteersResults from this study shall give rise to designing a future study on the…
ObjectivesPrimary:• To assess the effect of ethanol compared to placebo on a driving simulator performance tests;• To assess the effect of alprazolam compared to placebo on a driving simulator performance tests;Secondary:• To assess the effect of…
The objectives of the study are as follows:*1. To assess the effectiveness of inhaled PA101 delivered via eFlow high efficiency nebulizer for treating chronic cough. Improvements in chronic cough will be assessed by measuring the change from…
The aim of this research is to find out whether eating Broccocress®, a sprout vegetable rich in the substance sulforaphane, can counteract inflammation caused by, among other things, unhealthy food. More precisely, we are investigating whether…
The primary objective of this study is to investigate the effect of a 6-week colon-delivered multivitamin supplementation on the gut-brain axis in older adults, by assessing changes in brain function (working memory) as well as intestinal changes (…
PrimaryTo evaluate the efficacy of fezolinetant 45 mg versus placebo on the frequency of moderate to severe VMSKey secondaryTo evaluate the efficacy of fezolinetant 45 mg versus placebo on the severity of moderate to severe VMSSecondary• To evaluate…
To investigate the effectiveness of a personalized multi-domain lifestyle intervention compared to online access to general lifestyle-related health information on cognitive performance in older adults at risk of cognitive decline. Cognitive…
To compare the outcome of revascularisation the gastrointestinal arteries using covered stents compared to bare-metal stents in patients with CGI.