129 results
To compare the pharmacokinetics of sublingual testosterone cyclodextrin followed by buspirone as an encapsulated tablet with administration of testosterone and buspirone as one tablet designed to release the components in a specific time-frame.
Based on the literature study (encompassing literature on FFFFF, case descriptions of lone wolfs, and literature regarding different forms of aggression) specific hypotheses with regard to the role of freeze-fight-flight and focus (FFFF) in violent…
The primary aim of this study is to investigate the efficacy of MBT-DH in comparison to MBT-IOP. A secondary aim is to explore the cost-effectiveness and matching potential of various baseline variables that might help treatment selection procedures…
The study consits of *three parts1. Predictionmodel of the duration of sick leave due to CMD's 2. Predictionmodel for recurrences due to CMD's3. Qualitative research of experiences from workers with CMD's and working ad 1 How is the…
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
To report on (the age-dependency of) the long-term effect(s) of chronic SSRI treatment during adolescence or adulthood on the outgrowth and function of the 5-HT system, using state-of-the-art Magnetic Resonance Imaging (MRI) techniques and other,…
Primary: to study the frequency and characteristics of fatigue and cognitive disorders after minor stroke. Secondary: to gain more insight in the aetiology of post-stroke fatigue and evaluate the impact of post-stroke fatigue on personal and social…
Study 1: Examine how interparental and parent-child relationships in families who have experienced CSA differ from interparental and parent-child relationships in families who have not experienced CSA, and how these relational effects are related to…
Our aim is to determine the effect of APO* on activity and volume of the hippocampus, a core structure of Alzheimer pathology, at a young age. Specifically, we aim 1) to determine the effects of APOE e4 on hippocampal activation in the young general…
The primary objective of the current study is investigating whether AN patients and controls differ how they experience the shape and size of a rubber hand that during the Rubber Hand Illusion is incorporated in their body image, compared to how…
To investigate the effects of a single dose of fludrocortisone, a mineralocorticoid receptor agonist, on emotional information processing in healthy female participants.
This project aims to investigate the role of sleep on memory processing in PTSD. The primary aim of the study is to assess the effects of sleep architecture on emotional memory processing and neurocognitive functioning in subjects with and without…
Primary:to evaluate the safety and tolerability of EVP-6308 after single and multiple ascending dose administration in healthy subjects.Secondary:to determine the pharmacokinetics of EVP-6308 and select metabolites following single and multiple oral…
2. OBJECTIVESPrimary Objective: 1. Does conversion tremor show similar abnormal cerebral activation patterns compared to conversion pareses?Secondary Objective:1. Is decreased precuneus activity also present in conversion tremor?
To demonstrate the extent to which an intervention that combines treadmill training augmented by virtual reality (TT+VR) reduces fall risk, improves mobility and enhances cognitive function in a diverse group of older adults, compared to a treadmill…
Do patients with (recent onset, medicated) psychotic disorder (PDM), in persons at ultra high risk for later psychosis (UHR), in patients with schizophrenia who do not use anti-psychotics anymore (PDUM) report higher levels of trait anxiety (…
The current project is aimed at examining the reasons for not participating in preventive services systematically and to make an overview of possible solutions. A second goal is to make an overview of reasons for (not) participating in interventions…
To answer the question whether an intervention, aimed to reduce problem behavior, is more effective for a particular genetic subgroup of children, and why this might be. The current studie study gives insight into the moderating effects of specific…
Primary objective: To investigate whether sleep disturbances during pregnancy and/or in the perinatal period will predict postpartum psychopathology in women with an established diagnosis of bipolar disorder and/or a history of postpartum psychosis.…