129 results
To assess microglial activation in first episode patients with psychotic symptoms and first episode medication naïve patients with psychotic symptoms compared to healthy controls using the positron emission tomography (PET) tracer [11C]-R-PK11195.
The main goal of this study is to recruit and obtain magnetic resonance images in a large sample of bipolar patients and controls from the Netherlands, in order to find brain abnormalities specific for bipolar disorder. We will also perform genetic…
Our primary objective is to investigate the development of structural and functional connectivity in autism and ADHD in comparison to the typical development of connectivity. A secondary objective is to investigate the effects of ADHD and autism…
The aim of this study is the investigate genetic and environmental factors which make a person vulnerable to develop a pychosis and (in patients) affect the progression of a psychosis. A second objective is to investigate the effects of genetic and…
The aim of the proposed research is to assess, using multimodal fMRI, both functional (BOLD responses) and structural (white matter) cerebral characteristics of the human IELT. In turn, this could provide specific novel (neocortical) targets in the…
Aim of this study is to examine the mechanisms by which attachment style and emotion regulation relate to depressive symptoms and anxiety symptoms in a clinical and non-clinical Dutch population.
Primary aim:In recently traumatized individuals (at the latest on day ten post trauma exposure) with a high initial level of distress, we aim to assess the effectiveness of intranasal OT in preventing symptoms of PTSD at one months post intervention…
To investigate the short-term effectiveness of a 4 month manualized home-based behavioral treatment for referred children with ADHD, aged 6 to 13 years, who have responded insufficiently to first line treatment with medication or behavioral parent…
1) To study the predicitve value of fear acquisition and extinction mechanisms on treatment outcome in anxiety disordered patients. 2) To study pathological fear acquisition and extinction in anxiety disorders: what are the differences in…
This study focuses on collecting data on knowledge, attitudes, skills, experiences and needs related to sexuality and relational functioning in high-functioning Dutch boys with autism between 15 and 18 years old (up to and including 17). Data are…
The aim of this project is to elucidate the mechanisms underlying one of the most incapacitating psychiatric disorders, psychosis. Despite antipsychotic treatment, up to a third of patients with psychotic illness continue to experience significant…
The aim of the study is to investigate the effectiveness of the online intervention Etendebaas.nl for female patients with bulimia nervosa (BN), binge eating disorder (BED) and eating disorder not otherwise specified (EDNOS). The research questions…
The present study has the following objectives:1) Investigating the clinical utility of screening instruments. As a part of this objective, we will examine how several demographics (e.g. ethnicity) affect the assessment of autistic and other…
The primary objective of this study is to evaluate neurophysiologic changes of the pain centres of the brain (the differences in particular in the thalamus, primary and secondary somatosensory cortex, insula, anterior cingulate cortex and the motor…
BODY SCHEMAThe primary objective of the current study is investigating whether AN patients and controls differ in body schema. The first secondary objective of the current study is investigate whether there is a relation between body dissatisfaction…
The objective of the study is to answer the following research questions:1) What differences do exist in functional connectivity between patients with unipolar depression and healthy controls? 2) Can changes in functional connectivity be used as…
Primary: The primary objective of this study is to evaluate the long-term safety of SPD489 administered as adaily morning dose (30, 50, and 70mg) in the treatment of children and adolescents (6-17 years of ageinclusive at the time of consent in this…
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
We expect Collaborative Care to have a positive effect on functioning, amount and severity of symptoms, quality of life, costs, mastery, attitude to pharmacotherapy, and satisfaction with care. If effect of this intervention can be demonstrated we…
To do pilot research to investigate the possibilities of EEG and eyemovent studies on perceptual and social processing in baby's.