110 results
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
Objective: To investigate whether binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants or not.
The key objectives of this study are to identify both the genetic background and pathophysiological mechanisms that underlie CSC. To achieve this we will: 1) Perform genetic analysis and ophthalmological examination in a cohort of sporadic CSC…
The project consists of three concrete goals:1)Compare symptoms and patterns of fatigue of visually impaired adults with a control group of adults without a visualimpairment.2)Develop an intervention aimed at treating symptoms of fatigue in visually…
The objective of this study is to analyse the retinal oxygenation in adults with the Oxymap T1 in patients with amblyopia and untreated or treated (vitreo-) retinopathies and compare them to a reference group of healthy eyes of amblyopic and Coats…
Development and validation of the D-AI KIDS and the D-AI YA:Currently there is no standardized instrument that measures visually impaired children*s and young adults' participation based on the nine ICF-CY domains. The primary objective of this…
To study neuronal and ophthalmological characteristics of a newly detected clinical entity called slow vision which hampers visual perception and attention of the affected patients.
The objective of this study is to investigate the use of retinal oximetry in children, between five and seventeen years of age, with (vitreo-) retinopathies and oxygen-related diseases of the retina by means of an Oxymap T1 fundus camera.
The objective of the study is to map in a standardized way the phenotype of carriers with known LHON mutations. We want to study the natural course of persons with LHON mutations by examining patients several times. Further, we want to study a…
The primary objective of this study is:- To determine the potential difference in MT and RNFLT between treated and untreated patients with anisometropic or strabismic amblyopia. Secondary objectives are:- To determine the potential differences in MT…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
To study the efficiency of visual information processing in patients with retinal disorders.
The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In two secondary objectives, we will advance novel model-based neuroimaging data-analysis…
The primary statistical objective of this study is to describe mean differences in corneal staining (type and area), for OPTI-FREE EverMoist Multi-Purpose Disinfecting Solution compared to baseline.
Main objectives: 1. to investigate the prevalence of vision abnormalities in 9- and 10 year old children; 2. to investigate the percentage of these vision abnormalities that were detected the VOV screening programme;3. to investigate whether these…
Demonstrate superiority of NEVANAC® (nepafenac ophthalmic suspension) 0.1% relative to nepafenac vehicle based on the percentage of diabetic retinopathy patients who develop macular edema (defined as >=30% increase from pre-operative baseline…
Primary Objective: The aim of this study is to determine the specificity in *real life*, when screening is performed during regular optician visits. This specificity will depend on the specificity of the screening test, the frequency of other eye…
Development, optimization and implementation of retro-orbital fibroblast cultures in our laboratory.