36 results
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
The main objective is to determine whether the administration of allogeneic serum micro eye drops using the mu-Drop device is non-inferior to the conventional sized drops in terms of effectiveness and safety.
Primary Objectives: - Assess the feasibility and clinical value of 7T MR to provide a more detailed anatomic description of the anterior visual pathway in NFMA patients compared to conventional MRI. - Assess the feasibility of high-field MRI to…
In this study, we want to demonstrate that MPP is no less effective than MPP plus XRT.
Primary Objective:The primary objective of this study is to demonstrate the long-term (3 years) favorable visual acuity and adverse event outcomes for the Clareon IOL compared to historical SPE rates as reported in EN ISO 11979-7:2014.Secondary…
(1) To determine the influence of optical quality on peripheral retinal sensitivity (as measured with perimetry) for phakic and pseudophakic healthy eyes, (2) to compare the optical quality between healthy subjects and (phakic and pseudophakic) POAG…
To study the effect of the availability of a predictive uveitis model in the clinical setting on the 1 year visual outcome of patients.
To evaluate the natural progression of disease over time in USH1B patients using visual field testing and best corrected visual acuity.
To demonstrate whether a statistically significant difference exists between T2D patients with and without DR.
To establish the proportion of complete vitreoschisis removal with PVA.
To report the natural history of retinal degeneration in patients with biallelic mutations in the USH2A gene; to identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in USH2A-related retinal…
To compare, the perifoveal microvascular changes (non-perfusion areas) in the deep capillary plexus layer between Behçet patients with and without ocular involvement and control subjects, using OCT-A.
Primary Objective: The aim of this study is to assess the clinical value of intraoperative OCT (iOCT) for Descemet Membrane Endothelial Keratoplasty (DMEK) by comparing an iOCT-optimized surgical protocol (iOCT-p) with the current practice (CP-p),…
To examine the presence of structural and functional brain changes in glaucoma patients. Specifically, we are interested in the presence of glaucomatous functional brain changes that are beyond those that can be explained on the basis of propagated…
The primary objective of this study is to investigate the association between smartphone use and risk of myopia in teenagers.
Primary To evaluate the efficacy of Pegcetacoplan compared to sham injection in patients with GA secondary to AMD assessed by change in the total area of GA lesions from baseline as measured by FAF.Key SecondaryTo evaluate the efficacy of…
The primary objective of this study is to determine the effect of transsphenoidal adenomectomy on parameters of macular ganglion cell thickness and the PIPR in patients with optic chiasm compression. The main secondary objective is to assess the…
Primary Objective: To evaluate the safety and efficacy of 2 concentrations of Atropine Sulfate OphthalmicSolution (0.01% and 0.02%) compared to Vehicle (placebo) for slowing the progression of myopia inchildren over a 3-year treatment period.…
This exploratory study is designed to evaluate several depatuxizumab mafodotin-related OSE management strategies.The main objective of this trial is to estimate the percentage of subjects in each prophylactic treatment arm who require a change in…
The goal of this study is to characterize the natural course of IRDs that can potentially be modulated by future therapy. Second, this study aims to understand the relationship between various structural and functional biomarkers in potentially…