32 results
Primary:• To demonstrate that RTH258 6 mg is not inferior to aflibercept 2 mg with respect to the change in best-corrected visual acuity (BCVA) from Baseline to Week 48Secondary:• To demonstrate that RTH258 6 mg is not inferior to aflibercept 2 mg…
To determine whether corneal clearance is obtained with endothelial transplants of smaller size and/or lower endothelial cell counts.
The objective of this trial is to evaluate the safety and efficacy of the combination of Fovista® intravitreous administration with Avastin® compared to Avastin® monotherapy.
The major goal of this study is to develop a systematic and stepwise approach for dry eyes. First, it will be evaluated whether Tes glasses are a diagnostic tool for dry eye diseases. Second, it will be evaluated or it can make a distinction between…
A comparison of the PR-OCT and conventional ways of examination of patients, being slitlamp biomicrsocopy combined with stand alone SD-OCT, and fluorescein / ICG angiography, or glaucoma screening.
Primary ObjectivesThe primary objectives of this study are:* To evaluate the long-term efficacy outcomes following short-term exposure to rhIGF-1/rhIGFBP-3 versus standard neonatal care in Study ROPP-2008-01 (Section D) as assessed by ROP associated…
The key objectives of this study are to identify both the genetic background and pathophysiological mechanisms that underlie CSC. To achieve this we will: 1) Perform genetic analysis and ophthalmological examination in a cohort of sporadic CSC…
The primary objective of the study is to compare the accuracy in toric IOL alignment when using the VERIONTM Measurement Module and VERIONTM Digital Marker for alignment of the toric IOL or the conventional manual ink-marking procedure. The…
To demonstrate that FS laser aided keratoplasty for KC is superior to MALK.
The project consists of three concrete goals:1)Compare symptoms and patterns of fatigue of visually impaired adults with a control group of adults without a visualimpairment.2)Develop an intervention aimed at treating symptoms of fatigue in visually…
Long-term follow up of patients treated with limited PDT, for a symptomatic circumscribed choroidal hamangioma, in search of possible late unwanted side effects of PDT treatment and recurrence of leakage.
To measure the quality of peripheral visual field in healthy volunteers and the effect of different corrective lenses on the peripheral visual field.
The study will be performed in 2 parts, Parts A and B. The purpose of the study is to investigate to what extent BN201 is tolerated. It will also be investigated how quickly and to what extent BN201 is absorbed and eliminated from the body (this is…
The objective of this study is to analyse the retinal oxygenation in adults with the Oxymap T1 in patients with amblyopia and untreated or treated (vitreo-) retinopathies and compare them to a reference group of healthy eyes of amblyopic and Coats…
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
The purpose of this study is to collect additional safety and effectiveness of the InnFocus MicroShunt (MIDI Arrow) in subjects suffering from primary open angle glaucoma that are inadequately controlled on maximum tolerated medical therapy with…
Primary objectives1) To clarify which components of spatial remapping are impaired after damage to the posterior parietal cortex.2) To correlate spatial remapping abilities with scanpath quality in visual search.3) To examine whether different…
The primary objective of the study is to establish the ocular safety and tolerability, and systemic safety of 3 different concentrations of preservative-free PHMB in healthy subjects.
The objective of this study is to determine the light and dark adapation time and contrast sensitivity in changing background light conditions.
To study IVCM backscatter measurements as a usefull measurement to decide between surgical indications.