29 results
The objective of this study is to evaluate the efficacy and safety of adalimumab 80 mg loading dose followed by 40 mg dose given every other week (eow) subcutaneously (SC) starting at Week 1 compared with placebo as maintenance therapy in subjects…
To evaluate the long term safety, efficacy, predictability, stability, complications and patient satisfaction after implantation of Artisan phakic intraocular lenses for the correction of high degree myopia.
To assess the percentage of patients with at least one subtherapeutic infliximab trough serum concentration, being < 1 mg/l.To assess the percentage of patients positive for AIAs at a minimum of one timepoint.To assess the percentage of…
The objective of this study is to evaluate the efficacy and safety of adalimumab 80 mg loading dose followed by 40 mg dose given every other week (eow) subcutaneously (SC) starting at Week 1 compared with placebo in subjects with inactive non-…
To compare one dose of the short acting tropicamide combined with one dose of the longer acting cyclopentolate (c+t) with a double dose of the longer acting cyclopentolate (c+c). To develop a cycloplegics protocol that garantees optimal refractieve…
Evaluation of the CLIP strategy of glaucomatous loss
Primary objective:- To determine whether high dose vitamin D treatment in optic neuritis can reduce axonal loss as measured by OCT. Secondary objectives: - To investigate whether the occurrence of a second attack (defining clinically definite MS) is…
This study has the following goals: 1. Generation of normative values for full-field ERGs within single recording sessions according to ISCEV standard.2. To compare function (results of full-field ERG) with anatomy (retinal thickness on OCT) in…
The objective of this study is to make a comparison between six different cornea topography measurement systems.
1. To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.2. To determine whether this proposed…
Primary: To assess the effects of PRM-151 compared to placebo on the success of trabeculectomy by reducing post-surgical scarring in glaucoma patients who have undergone primary trabeculectomy, evaluated at day 120.Secondary: To assess the safety…
The objectives of this study are to assess and compare bilateral uncorrected distance visual acuity and distance spectacle independence post bilateral implantation of AcrySof Toric IOLs and monofocal IOLs.
To create a registry for paediatric patients with iris-fixated or posterior IOL*s, and the assessment of the long-term effects of implanted, artificial lenses in children.
The objectives of this study are to demonstrate that Nepafenac Ophthalmic Suspension, 0.3% is not inferior to Nepafenac Ophthalmic Suspension, 0.1% (NEVANAC®); Nepafenac Ophthalmic Suspension, 0.3% is superior to Nepafenac 0.3% Vehicle and NEVANAC…
The aim of this study is to determine whether the hydration status influences the RNFL thickness.
The objective of this study is to prospectively evaluate postoperative visual outcome in a series of patients bilaterally implanted with the AcrySof® IQ ReSTOR® Aspheric +3 D multifocal IOL versus those bilaterally implanted with the LENTIS® Mplus…
The purpose of this clinical trial is to evaluate the clinical performance of the PACT procedure in lowering intra-ocular pressure in subjects with elevated intra-ocular pressure, as a function of glaucoma or ocular hypertension.
To determine the beneficial effect of a single dose of 150 µg clonidine as an adjuvant to chirocaine in retrobulbar block.
Primary Objective:* To study the impact of playing wind instruments for the development of OHT and (progression of) glaucoma.Secondary Objective(s): * To study the risk factors for the development of OHT and glaucoma in professional musicians.* To…
What is the contribution of the different variations in the C1-inhibitor gene to the disease AMD?