41 results
Hypothesis: Percutaneous nephrostomy is non inferior to retrograde double J catheter regarding time to clinical recovery. Secondly, patient reported outcome measures (PROMS) comparing treatment room and OR settings of drainage procedures will most…
The aim of this trial is therefore to determine the effects on mortality and rehospitalization rate of a targeted correction of plasma sodium concentration in addition to current standard care in hospitalized hyponatremic patients.
To assess the timed effects of a matched acute oral sodium load (in the absence or presence of GLP-1 receptor agonist) or an acute intravenous sodium load in T2DM patients with/without renal impairment on urinary sodium excretion after 24h,…
The primary objective is to demonstrate that semaglutide delays the progression of renal impairment and lowers the risk of renal and cardiovascular mortality compared to placebo, both added to standard-of-care, in subjects with type 2 diabetes and…
Comparison of functional outcome of PD catheters in the two placement techniques.Describing 30 day mortality and short and middle term complications.
By performing a low-dose CT of the thorax in patients with primary spontaneous pneumothorax (PSP) the typical pulmonary abnormalities are detected related to the mutation in the folliculine gene. In this way the Birt-Hogg-Dube syndrome can be…
(1) To develop patient-specific hemodynamic models of arteriovenous grafts at multiple time points after surgery, thereby including venous outflow stenosis; (2) to determine the critical stenosis severity at which the arteriovenous graft is at risk…
Determining the added value of cone-beam computed tomography in percutaneous nephrolithotomy, by measuring differences in the stone-free rates for patients with cases in which a cone-beam CT-scanner is used versus patients with cases in which no…
The main objective of this trial is to determine whether reusable catheters are not less efficient as single use catheters, measured by symptomatic UTIs. Secondary objectives are adverse events like hospital admissions due to UTIs, urethral damage/…
PrimaryTo evaluate the effect of DCR PHXC on estimated glomerular filtration rate (eGFR) in participants with PH1Secondary:To identify the proportion of participants with normalized or nearnormalized 24 hour urinary oxalate (Uox)2. To identify the…
To compare surgical strategies for vascular access creation in elderly hemodialysis patients.
Primary Efficacy objective: The purpose of the study is to test the efficacy of the Neuspera Implantable SNS System for treatment of urinary urgency incontinence Primary safety objective: The primary safety objective of the study is to assess the…
The primary objective of the study is to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical functioning. The secondary objectives of the study are to assess the longitudinal effects of…
To assess long-term outcomes in low-immunological risk renal transplant patients beyond one year after transplantation using tacrolimus monotherapy versus tacrolimus with mycophenolate mofetil.
The primary objective of this study is to determine histological ablative efficacy by absence of vital (tumour) cells in the treated prostate zone with (multi)fibre setup in men with PCa scheduled for radical prostatectomy. The secondary objectives…
To evaluate the feasibility of TBER-guided ultrafiltration (UF) in patients on HD, using an end-of-HD TBER score of +2 SD as the optimal target.
Development of a predictive test for r-FSGS at the individual level of a patient and kidney donor with FSGS.
The main objective is to investigate whether the variant indeed cause mitochondrial dysfunction leading to the observed phenotype, including characterization of the pathophysiology.
Primary:To assess the efficacy of DCR-PHXC in reducing urinary oxalate burden in patients with PH (types 1 and 2)Key Secondary:To assess the efficacy of DCR-PHXC in reducing urinary oxalate burden over time in patients with PHSecondary:1. To…
Primary objective:* To compare the rates of complete recovery (alive, free of dialysis and return of serum creatinine to <150% of reference baseline; equivalent to acute kidney disease (AKD) category 0) at Day 14 between the Reltecimod-…