49 results
The objectives of this study are to determine the prevalence of dRTA, osteoporosis and nephrolithiasis in patients with SS. We also try to elucidate the mechanism which is responsible for developing dRTA in patients with SS. The role of auto…
- To evaluate the demographic, clinical and genetic characteristics of all known patients with a diagnosis of cystinuria and cystine nephrolithiasis in the Netherlands.- To evaluate the relationship between genotype and phenotype of all known…
To study the effect of acetazolamide on lithium-induced NDI.
Objectives:The objective of the trial is to evaluate efficacy and safety of two different doses of Nefecon® in the treatment of patients with primary IgA nephropathy (IgAN) at risk of developing end-stage renal disease, under rigorous blood pressure…
The Virtue male sling study in Europe is designed to assess efficacy and safety of the Virtue® Male Sling.
To evaluate the accuracy and adverse events of combined use of minimal invasive optical coherence tomography (OCT) to differentiate normal tissue from (different types of) malignant tissue in kidneys.
First, to demonstrate whether Lanreotide attenuates progression of the renal phenotype in ADPKD patients as measured by change in rate of renal function decline and change in renal volume. Second, to demonstrate whether Lanreotide modifies…
To confirm previous study results using a Solace Balloon and to support future marketing efforts in the European Union and provide data for publications.
To assess the efficacy of Mirabegron 50mg versus Solifenacin 5mg in the treatment of subjects with OAB who were dissatisfied with their treatment due to lack of efficacy.
To validate a diagnostic panel existing of MRI, CEUS, and FNA, which can differentiate benign pathology from malignant pathology of complex renal cysts.
To identify objective parameters to characterize Non Voiding Activity (NVA) in healthy and OAB subjects using high resolution urodynamic assessmentNVA are changes of pressure in the bladder lumen. These changes are measured as detrusor pressure (…
This study aims at understanding the circadian disruption in chronic hemodialysis patients and provide a molecular basis for the etiology of sleep-wake cycle disturbances. The hypothesis that the circadian clock is disturbed in chronic hemodialysis…
Gain insight in the anatomy and organisation of the sacral plexus in children with NB and congenital spinal or sacral anomalies. Possible findings can be compared with the results of the healthy subjects, in order to be able to relate findings to…
Clarifying the qualitative and quantitative aspects of the T cell response targeting and controlling polyomavirus BKV.
To test the efficacy of renal sympathetic denervation therapy with a special focus on preservation of renal allograft function.
Primary Objective: -To compare metabolic activity and efficiency directly after transplantation in living and deceased donor kidney grafts. Secondary Objective(s): -To assess whether the contribution of aerobic and anaerobic metabolism differs…
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
Primary : To evaluate the safety and tolerability of single oral doses of LY3045697 administered to healthy subjects Secondary : To investigate the pharmacokinetics of single oral doses of LY3045697 administered to healthy subjects Exploratory : To…
To evaluate the efficacy, safety and PK of solifenacin succinate suspension after multiple dose administration.
The aim of this study is to identify the degree and direction of fluctuation from one to another renal function group within 2 months after discharge from hospital. In addition, prevalence of adaptations of the prescribed drugs that should result…