289 results
We aim to study the effectiveness of an intervention provided by nurse practitioners who will:- Provide conversations on Advance care planning (ACP);- Coordinate care based on patients needs at advanced stage;
Primary objective:To assess the safety and tolerability of single doses of i.v. administered NX210.Secondary objective:To assess the PK of NX210 via its metabolite NX210c in plasma after single doses of i.v. administered NX210.Exploratory objectives…
The primary objective of this study is to assess the feasibility of placing neurostimulator leads in the epidural space based on intraoperatively recorded ECAPS
The aim of this study is to investigate the effect of discrete vibrotactile feedback of mediolateral weight shift and step initiation for complete SCI patients on the use of an exoskeleton.
We aim to investigate the renal hemodynamic effects of empagliflozin in people with either preserved or impaired renal function with T2DM and people with impaired renal function without T2DM, all with and without adenosine blockade.
INCbase is a research platform to collect prospective standardized longitudinal data from a worldwide population of patients with suspected CIDP. One of the first objectives of the Inflammatory Neuropathy Consortium Base (INCbase) is to develop a…
Primary objectives:1. To determine the gene frequencies of HLA-A, B, C, DR and DQ in patients with autoimmune encephalitis and compare this to the general Dutch population. 2. To determine genetic risk factors for the development of autoimmune…
To gain insight into how people with CP of 40 years or older experience their citizenship and how these adults can be supported in their citizenship. How their citizenship has changed over time. To develop posters for rehabilitation practice to gain…
To be able to further investigate the benefit of these interfascial plane blocks we want to perform a randomized controlled trial. Since the effect on postoperative pain of PECS II was similar to PECS I + ESB, we only use the PECS II as an…
Primary objective:To evaluate the safety and tolerability of a single dose of DCR-PHXC in patients with PH3Secondary objectives:To characterize the plasma PK of a single dose of DCR-PHXC in patients with PH3To assess the efficacy of a single dose of…
To compare the quality of life of patients with NMD receiving capability care versus usual care, using a before-after design.
ObjectivesPrimary* To evaluate the efficacy of mirabegron in children (5 to < 18 years of age) with OABSecondary* To evaluate the efficacy of mirabegron in children (5 to < 18 years of age) with OAB* To evaluate the safety and…
1) Identify and describe different trajectories in the clinical course of people with acute neck pain. 2) Assess which biological-, psychosocial factors and treatments characteristics, differ between, and are most associated with the different…
The primary objective of this study is to study whether driving ability may be affected in de novo, treatment naïve PD patients, by comparing their driving simulator performance to age- and sex-matched healthy controls (HC). The secondary objective…
- To evaluate the effect of magnesium and phosphate supplementation on intracellular levels of magnesium and phosphate determined with different techniques.- To determine if symptoms are related to intracellular levels of magnesium or phosphate.
To objectively determine the severity of CTD related physical impairments, complaints and difficulties during participation in daily life activities. An additional study objective is: - To determine risk factors for the development of health…
The objective of this study is to accurately determine the kinematics of healthy subjects to be able to compare them with patients suffering from patellofemoral instability, by scanning volunteers without knee complaints using 4D dynamic CT imaging…
The relation between pre-operative parameters and patient satisfaction after Total Knee Arthroplasty
The primary objective of this study is to identify correlations between pre-operative, i.e. biomechanical and planning, parameters and patient satisfaction after TKA surgery.
Optimisation of MRI research protocols including respiratory challenges with the RespirActTM.
Does performance on a fatiguing dual task task in patients with FSM decline more compared to patients with AIS? What are the differences in cognitive functioning and motor fatigue between FSM, AIS and healthy controls? What is the relation between…