152 results
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
The aim of this study is to assess the change of ammonia exhaled in Helicobacter pylori (HP) positive patients compared with patients that are not HP infected after urea administration. In principle, in this pilot study, the results of Kearney et al…
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
The aim of this randomized controlled trial is to determine the affect of screening on the Gastrointestinal symptoms (GIS) and Health Related Quality of Life (HRQL) in asymptomatic first degree relatives of CD patients. On the basis of the results,…
Determine normal ADC values and the reproducibility of the ADC values in normal liver tissue and colorectal liver metastases in a multicentre trial. Determine the effect of lesion volume on reproducibility of the ADC values.
Primary objective: to investigate the intra- and interfraction motility of the CTV (the primary tumor as well as any affected celiac lymph nodes) in radiotherapy for esophageal cancer, and to determine adequate CTV-ITV margins.Secondary objective:…
To identify relevant geriatric assesment tests to develop a clinical instrument for predicting tolerance defined as the change of developing a complication in elderly patients (>=70 years) with a coloncarcinoma that recieve surgical treatment…
In this study, we first intend to investigate the optimal time point for measurement of hypoxia in esophageal, pancreatic and rectal cancer using 18F-HX4-PET and then assess reproducibility of hypoxia measurements in these tumor types.
Implementation of a biobank infrastructure to facilitate development and improvement of screening markers for colorectal neoplasia. New biomarkers will be compared to state of the art tests, e.g. currently FIT.
To assess whether a decrease in heart volume is accompanied by changes in myocardial strain, strain rate, inferior vena cava diameter and blood levels of NT-proBNP and troponins.
To develop a method to determine Infliximab in feces
The aim of this study is to determine the population and functionality dynamics of the microbiota in ileostomy subjects.
To investigate whether bowel relaxation, induced by administration of hyoscine N-butylbromide, improves the detection, removal and colllection of lcolonic polyps during colonoscopy
This study will contribute to improving quality of care for cancer survivors, since sexual problems seem to be profound but not always discussed with patients. Patients are now often insufficiently informed and do not know how to interpret their…
In the Netherlands, gum chewing has not been incorporated in the standard postoperative care after intra-abdominal surgery. Therefore a multi-center RCT was set up to evaluate the influence of gum chewing on the development of ileus. Our null…
To determine the association between shLAIR-1/ hLAIR-2 levels in urine samples and clinical and endoscopic disease activity in patients with UC and CD
Primary endpoint:- Successful desensitization for Mesalazine in ulcerative colitis patients with a presumed history of intolerance for Mesalazine. Secondary endpoint:- To investigate if a presumed intolerance for Mesalazine may be reproducible in a…
The overall objective of this study is an improvement in (early) diagnosis of NEC and its life-threatening complications, thus to be able to detect children who are *at risk* for NEC and its complications as early as possible. To this end we will as…
Primary: To investigate if there is a correlation between findings of transabdominal ultrasound measurement of the rectum and rectal digital examination. Secondary: To investigate if there is a correlation between an enlarged rectum (diameter &…
The main objective of this study is to obtain normal values for high-resolution manometry. The second objective is to investigate the inter- and intra-individual variability of the measured parameters.