99 results
(1) To compare adenoma miss rates (AMR) between Endocuff Vision-assisted colonoscopy (EAC) and conventionalcolonoscopy (CC)(2) To compare adenoma detection rates (ADR) between EAC and CC(3) To assess whether a proposed increased ADR and reduced AMR…
To study the effect size of FMT after a 3 weeks course of budesonide as induction therapy in patients with active ulcerative colitis despite previous therapy. The purpose of the pre-treatment is to reduce active inflammation prior to donor feces…
To assess the correlation between the presence of GIP in urine/ faeces and symptoms after a single dose gluten provocation (mimicking the daily risk of gluten ingestion) in patients with coeliac disease adhering to a strict gluten-free diet.
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
To investigate whether there is a difference in gastric volume over time after ingestion of cow milk between lactose tolerant, habitual milk consumers reporting no GI symptoms and non-habitual milk consumers reporting GI symptoms after milk…
We hypothesized that mesothelioma lysate–pulsed dendritic cell immunotherapy induces an immune response that is beneficial for pancreatic cancer.
To evaluate the effect of dietary therapy with a probiotic supplement on the composition of stool microbiome in fatigued IBD patients with quiescent diseaseTo define the effect of dietary therapy with a probiotic supplement on serum inflammatory…
To investigate whether there are differences in single nucleotide polymorphism*s (SNPs), circulating tumor DNA (ctDNA), micro RNA (miRNA) and immune profiles between responders and non-responders to FOLFIRINOX chemotherapy and between patients who…
To investigate the changes in fistula healing and quality of life after hyperbaric oxygen therapy in patients with Crohn's disease, and to assess the feasibility and safety of the treatment in these patients.
To assess the effect of Ziverel on esophageal sensitivity to acid, mucosal barrier function and reflux symptoms in patients with PPI-refractory reflux symptoms.
The aim of present study is to investigate if adapting the dosing factor based on TBW and therefore the CM volume to the tube voltage used, results in a more homogeneous liver enhancement. We hope to find a more homogeneous enhancement between…
The primary aim is to explore the system-wide leukocyte composition in order to identify and quantify immune subsets in patients with alcoholic, biliary and idiopathic AP. Secondary we aim to identify subsets prognostic for the severity of the…
Safety objective: To evaluate the safety and tolerability of UTTR1147AExploratory Efficacy Objective: To evaluate the efficacy of UTTR1147AExploratory Pharmacokinetic Objective: To evaluate potential relationships between long-term drug exposure and…
The aim of this research is to investigate whether it is feasible and safe to treat operated pancreatic cancer patients who have completed standard of care treatment with dendritic cell immunotherapy using dendritic cells loaded with autologous…
The effect of pelvic floor physiotherapy with biofeedback in patients with anal fissure and pelvic floor dysfunction.
The effect of body composition on the farmacokinetiek IFX in patients with inflammtoy bowel disease;
The aim of the studie is to determine the correlation between fat mass end the IFX concentration. Primary research question:What is the effect of fat mass percentage, measured by a validated scale, and secundaire skinfold measurement, waist…
The primary objective is to assess the effect of an anti-inflammatory diet as add-on therapy on faecal calprotectin in patients with inflammatory bowel disease. Secondary objectives will be to assess the effect of the diet on clinical disease…
Primary Objective: * What is the influence of alterations in the intestinal microbiome composition on the course of disease in patients with IBD?Secondary Objective(s): * Is the intestinal microbiome composition associated to fatigue scores?* Is the…
The purpose of this study is to investigate how quickly and to what extent the new compound PL8177 is absorbed and eliminated from the body (this is called pharmacokinetics) when it is administered to healthy volunteers. PL8177 will be labelled with…
To determine if inhibition with GPB can provide a significant reduction in the accumulation of systemically administered Ga-PSMA in salivary glands on PET/CT, with the aim to determine if GPB can prevent toxicity from Lu-PSMA or other…