93 results
In this prospective observational cohort study we aim to study the potential clinical consequences of antibiotic use in early life, by focussing on the incidence of eczema, as well as food allergy, upper respiratory tract infections (URTI), lower…
The STEM study presented here aims to increase our knowledge of the most common intestinal, gastric and liver epithelial diseases with the ultimate goal to treat these disorders. Particularly, children that have severe malfunction of their…
Primary Objective: disease related treatment failure.Secondary Objectives: Overall survival, CRM negative (margin > 1 mm) rate, Pathological complete response (pCR) rate, Short and long-term toxicity, Surgical complications, Quality of life.…
The primary objective is to determine the number of subjects that experience a decrease in CDAI (Crohn*s Disease Activity Index) of at least 70 points by the Week 8 or Week 12 assessment.
Optimization of the supplementation of vitamins and minerals1. In patients who received a gastric banding for treatment for their morbid obesitya. Reduction of iron deficiencyb. Reduction of Vitamin B12 deficiencyc. Reduced Vitamin D deficiency2. In…
The primary objective is to generate genome-wide miRNA profiles of patient material (tissue samples and blood). The secondary objectives are to compare miRNA expression profiles to investigate what role differences in miRNA expression have in the…
The primary objective is to determine whether PF 00547659 alters central nervous system immune surveillance in subjects with active, moderate to severe Crohn*s disease or active, moderate to severe Ulcerative Colitis by altering the absolute…
Identification of the underlying genes of MMIHS
The aim of our project is in-depth characterization of the microbiota components both adjacent to and within the mucosa in patients with IBD, by applying novel high-throughput analysis technology in a global description strategy approach.…
To compare the protein profile of Barrett*s mucosa with and without early neoplasia in ER specimens in epithelial and stroma aiming to identify a biomarker indicating presence of early neoplasia in BE.
To perform a human pilot study to prove the hypothesis that a hybrid transgastric cholecystectomy is a safe procedure.
The aim of this study is to answer the question if RFA is an effective treatment modality in the long term, for patients with Barrett's esophagus containing HGIN or EC.
Study the very long-term efficacy (regarding reflux control) of antireflux surgery in children with severe GERD.
To investigate the safety and efficacy of a biodegradable esophageal stent during neoadjuvant therapy of patients diagnosed with resectable esophageal carcinoma.
The primary objective is to evaluate the efficacy of prucalopride compared to placebo for the treatment of functional constipation in a paediatric population, aged *6 months to <18 years. Secondary objectives include:1. Investigation of the…
Project description:A controlled randomized multicentre prospective clinical trial of 12 months duration at 5 centres. To evaluate and compare appliance of porous titanium granules (PTG) during surgical treatment of peri-implant osseous defects of…
To determine the association between shLAIR-1/ hLAIR-2 levels in urine samples and clinical and endoscopic disease activity in patients with UC and CD
Purpose:We like to determine the movement of the intestinal contents to measure the peristaltic movement/ motility.
To investigate the feasibility of imaging and measuring enhancement of colorectal cancers and polyps using iodine mapping after acquiring dual energy abdominal CT scan with intravenous iodine contrast in patients without bowel preparation.
Primary Objective: The proposed project involves a phase II study to investigate the feasibility and safety of radiofrequency ablation in irresectable locally advanced pancreatic cancer. Secondary Objectives: Secondary objectives of the study are…