86 results
The aim of this study is to gain insight in the mechanisms that may be involved in the effects of plant sterol drinks on gastric emptying and gallbladder motility. In order to test this, we compare the different effects of the consumption of a plant…
The main objective of this study is to obtain normal values for high-resolution manometry. The second objective is to investigate the inter- and intra-individual variability of the measured parameters.
To compare Savary dilation with saline 0.9% injections (placebo) with Savary dilation with triamcinolon injections in patients with benign anastomotic esophageal strictures
To compare migration rate to the stomach or esophagus of clip-assisted endoscopic duodenal feeding tube placement with non clip-assisted endoscopic duodenal tube placement.
We would like to conduct a RCT to confirm the hernia prevention effect of a mesh, however in a slightly different position, with a different mesh and with all types of stomas. In addition, we want to measure the possible benefit in terms of quality…
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…
To develop a simplified HALO90 ablation protocol at the same energy level and with compared efficacy and safety as the current protocol.
The primary objective of the study is to demonstrate safety and efficacy of the ALIMAXX-B* covered biliary stent.The secondary objective of the study is to evaluate technical success of stent placement, , re-interventions and time to occlusion.
To investigate a) the functional role of chloride secretion in constipated adults (Ussing chamber studies) and b) inventory possible aberrancies in in situ ClC-2/ CFTR expression levels by immuno-histochemistry staining techniques.
To compare the sensitivity and specificity of MR colongraphy with that of CT colonography for the detection of colonic neoplasms, compared to colonoscopy as "gold standard".
Patients in whom a permanent (end) colostomy is created in (semi) elective setting are randomised between the placement of a polypropylene mesh during stoma creation and the classic method without a mesh. Primary aim: Does the use of a lightweight…
The aim of this study is to compare LPM with OPM with respect to clinical benefits or disadvantages of LPM in children with hypertrophic pyloric stenosis.
To investigate the influence of left and right lateral position on the onset of TLESRs and GER and the underlying mechanisms during and after a test meal in GERD patients compared to healthy controls.
In patients with BO undergoing surveillance or work-up endoscopy for early neoplasia, we aim to evaluate if EQMI, consisting of ETMI combined with pCLE, increases the accurary of detecting early neoplasia (study phase 1). In addition, we aim to…
The first objective of this integrated trial (LOLA) is to determine whether laparoscopic lavage leads to better clinical outcomes compared to sigmoidectomy in patients with perforated diverticulitis with purulent peritonitis in terms of mortality…
Primary objective: To explore whether prolonged moderate alcohol consumption affects in vivo cytokine response after a low dose of LPS in young, normal-weight men.Secondary objectives: To explore whether prolonged moderate alcohol consumption-…
The aim of the study is to assess the accuracy and feasibility of contrast enhanced ultrasonography (CE-US), in the primary diagnosis and relapse during follow up of small bowel CD, compared to MR enterography. Furthermore we attempt to determine…
To study the diversity and functionality of intestinal microbiota of patients with IBS over time in comparison with asymptomatic controls.
The aim of the study is to evaluate and develop new diagnostic tools for an accurate diagnosis of IC:Primary objective: to test whether mucosal oxygen saturation has added value to endoscopy and histological examination. Secondary objective: to test…
The aim of this randomized controlled study is to compare two surveillance strategies with respect to their accuracy in colonoscopic surveillance in IBD patients.