37 results
The aim of this study is to retrieve extra measurements by Nexfin and laboratory testing in the per- and postoperative period. Can the use of Nexfin contribute in the generation of meaningful data to get an idea of the hemodynamic state of the…
Primary objective is to compare physical activity (time spent in moderate to vigorous activity and physical activity level) and exercise capacity (VO2 peak) in children after OLT with published data of healthy controls.Secondary objective is to…
To confirm that loss of gut wall integrity is associated with the development of biliary atresia and to investigate possible hypoxia in the liver/bile ducts in children with biliary atresia using NIRS
To investigate the in vitro effect of both pro- and anticoagulation therapy on thrombin generation by Calibrated Automated Thrombography in plasma from patients with cirrhosis undergoing liver transplantation.
The aim of this study is to compare the image quality, diagnostic confidence and patient discomfort when using either positive (50 ml Télébrix Gastro + 950 ml water ) or negative 1000 ml water only in outpatients undergoing a contrast-enhanced…
To investigate the origin of BA we will assess which TLR(s) is/are activated. To test the hypothesis that during development of BA and associated liver fibrosis there is a *leaky gut* and/or a change in microbiome we will use human material to…
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
The objective of this study is to gain insight in HIV infected children in the AMC in:.- the prevalence and clinical signs of livertoxicity - an association between the different compounds of combination anti-retroviral therapy (cART) and…
To demonstrate that extended postoperative antibiotic treatment does not decrease the infectious complication rate in laparoscopic cholecystectomy for acute cholecystitis.
To evaluate the prevalence of gastrointestinal ischemia in patients with acute and chronic non-cirrhotic, non-malignant PVT.
This study will focus on the positive and negative psychological consequences of organ transplantation in Dutch organ transplant recipients. The study will describe on posttraumatic stress and posttraumatic growth after organ transplantation, their…
Main goal: In this non-invasive pilot study, we want to investigate whether these techniques can discriminate between healthy livers and livers with cirrhosis. For the new techniques to be applied as an alternative for biopsy, the output values of…
To study the effect of peginterferon alpha and ribavirin on spermatozoa
To demonstrate and compare expression of CCL25 and CCR9+ lymphocytes in peripheral blood and colon of PSC-, PSC/IBD-, IBD-, gastroenteritis patients and controls.
This study aims to investigate neurodevelopment in primary school children surviving biliary atresia when compared to a healthy reference group. Second aim is to identify prognostic factors associated with a worse outcome in these children.
A proof-of-principle study to test whether an environmental factor, i.e. here IFNα treatment, induces epigenetic alterations of certain genes in blood lymphocytes and whether these alterations correlate with the severity of psychiatric symptoms, i.e…
The aim of this study is: 1) to determine the burden of ERCP in patients undergoing ERCP (descriptive study) and 2) to determine patients preferences for treatment strategy of CBDS (Discrete Choice Experiments).
Validation and quantification of 3.0 Tesla 1H *MRS for the assessment of hepatic steatosis in patients with non alcoholic fatty liver disease and patients chronically infected with hepatitis C. Is there a close correlation between the 1H *MRS…
Assessment of intra en inter reproducibility of 3.0 Tesla proton magnetic resonance spectroscopy in assessing hepatic steatosis. Reproducibility of visible peaks in water unsuppressed and suppressed MR spectra.
To study the correlation between histology and elastography in patients with elevated liver enzymes more than two times normal upper limit and the suspection of liver fibrosis or cirrhosis treated with MTX from the department Rheumatology and…