8 results
To show that treatment with SUBLIVAC® Grasses is clinically effective by means of reduction in allergic symptoms and/or use of allergic symptomatic medication in subjects suffering from IgE mediated allergic complaints triggered by grass pollen.
1. To investigate whether the currently used hay fever forecast correlates with the symptoms that grass pollen allergic patients report directly using a new communication system that allows direct control, and whether the model can be improved.2.…
To detect B-cell differentiation and maturation defects in patients with antibody deficiency syndromes of unknown origin (CVID, SAD), which are predictive for clinical complicationsTo detect and sequence candidate genes in subgroups of patients with…
The main objective is to identify a difference in mRNA expression level of IFN and IFN related genes between Down Syndrome children and a control group of healthy children (siblings). The secondary objective is to identify a relationship between…
The research strives for a large group of homogeneous AID patients, so that a powerful association study can be performed to detect genetic risk factors. These factors can be shared by several AIZ, or be specific is for a single AID. The aim of this…
In this pilot study the effects of exercise on muscle energetics in the proximal muscle groups of the legs with patients with Juvenile Dermatomyositis will be cross-sectional studied. This will be done with an exercise test using a recumbent bicycle…
Primary: Dose finding for a twice daily regimen for PSZ as prophylactic treatment in children with CGD, based on the exposure to PSZ measured by PSZ trough levels.Secondary:To determine the tolerability of PSZ as prophylactic treatment in children…
First, to develop a diagnostic method for non-infectious uveitis in childhood. Second, to analyze iris and ciliary body tissues of children with uveitis on the presents of inflammatory infiltrate. The results of this study will contribute in the…