89 results
To determinate the efficacy and safety of golimumab in patients with psoriatic arthritis in daily clinical practice prospectively. In addition, the effect of treatment with golimumab on the lipid profile will be monitored during this study and…
This study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites. Results will help clinicians develop a standardized initial approach that prolongs survival and optimizes quality of…
The objective of the current study is to determine and describe the level of physical fitness and the level of physical activity in Dutch children and adolescents after burn injury. With this a scientific fundament can be established for further…
The primary objective of this study is to compare the therapeutical effect on atopic dermatitis of a standard used emollient (Unguentum leniens FNA) compared to a skin barrier repair cream (Dermalex Eczema), assessed by clinical and subjective…
The main objectives of this study are to investigate 1) in vivo dermal absorption of Ag ions from the Silverwear ® garments in healthy versus atopic skin, 2) effect of dermal exposure to Silverwear ® garments on release of inflammatory cytokines in…
To investigate the possibility to measure non-invasively perfusion and oxygenation in static physiological conditions in the lower leg using MSOT.
The main objective of this study is to assess the in vivo efficacy of a skin protecting cream against skin irritation experimentally induced by sodium lauryl sulphate. Next, we aim to investigate whether the protective effect differs between…
Investigate how physical fitness and activity evolve over time in paediatric burn patients, also in relation to function.
This single-center investigation will assess the prevalence of psoriasis in a population of patients with hepatitis C and compare the prevalence in those patients receiving pegylated interferon-* therapy to those not receiving pegylated interferon…
The major aim is to apply deep sequencing technology to obtain a detailed unbiased overview of the bacterial microbiome of human skin. This will be performed in healthy individuals, psoriasis patients and atopic dermatitis patients. Furthermore, we…
Prevalence of Tinea Pedis (athlete's foot) in people with intellectual disability in The Netherlands
Study into the prevalence of Tinea Pedis in intellectually disabled people who receive care from one of four care providers in The Netherlands, either living in the community or in a centralised location. Study into the prevalence of the different…
By means of this in vivo study, we try to non-invasively get insights into the pharmacokinetics of PPD applied to the human skin. By studying penetration rate, penetration depth, allocation to different skin departments (stratum corneum, epidermis,…
Aim of the studyIn addition to the aims of the compassionate use protocol.To study:1. hypothalamic structure before and during leptin therapy2. hypothalamic function before and during leptin therapy
The present research project is directed at delivering further evidence for the mechanisms underlying generalized and symptom-specific sensitization in patients with chronic pain and itching. For this purpose, 4 experiments are set up to provide…
A pilot-study to the feasibility of a simple self-patchtest with a PPD containing hair-dye solution. The aim is to investigate whether a 30-minutes application of a patch-test gives a positive reaction in individuals who have a proven contact…
The primary goal is investigating the number of women that have lymphedema five years after the treatment for breast cancer. In the describing part of this study, the focus will be on the correlation between lymphedema and 1) surgical treatment, 2)…
The objective of the study is to assess the long-term safety of tacrolimus ointment 0.03% or 0.1% in the treatment of subjects with atopic dermatitis under actual use conditions, including the risk of developing cutaneous or systemic malignancies.…
The goal of this study is to validate and interpret a new HRQOL instrument and to analyse commonly used outcome measurements (PGA, PtGA) in dermatology.
Primary Objective: To show superiority of the novel fixtures compared to standard fixtures regarding stability of the implants measured as ISQ values.Secondary Objectives: 1. To compare the long time survival of the standard fixtures and abutments…
1) To determine the prevalence and the sensitivity for various antibiotics of Staphylococcus aureus in the nose (carrier) of patients visiting the outpatient department of Dermatology.2) To determine the prevalence and the sensitivity for various…