53 results
To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with
The primary objective To assess the effectiveness of an intervention program, consisting of provision of skin care products and regular group feedback, on the skin condition in health care workers The secondary objectiveTo assess whether this…
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
Primary:To determine the prevalence of pruritis in patients with hidradenitis suppurativa.Secondary:- to evaluate pruritis severity and its effect on three elements of daily activities;- to evaluate differences in extensiveness of HS in relation to…
Primary objective- To explore the pharmacodynamic effects of topically applied IMQ (in combination with or without TS) - To identify dose-response relationship of topically applied IMQ Secondary objective- To assess safety and tolerability of…
The aim of the project is to study the effect of KY1005-2D10 on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
Determine the relationship between stratum corneum lipids (and their enzymes) and inflammatory markers in patients with AE. This is achieved by measuring:i) The SC lipid matrix and bound lipids, focussing on ceramides and its biosynthesis (i.e. the…
Primary:• To demonstrate the therapeutic equivalence of ONS-3010 (adalimumab biosimilar) compared toHumira® (adalimumab) in patients with plaque psoriasis Secondary:• To assess the safety, tolerability, and immunogenicity of ONS-3010 compared to…
Assess feasibility of development of skin colour independent assessment of skin AGE accumulation by measurement of skin autofluorescence in persons with dark skin
With this pilot feasibility study, the feasibility of and satisfaction with an eHealth and serious gaming training based on psychological expectancy mechanisms are evaluated.
The aim of the project is to study the effect of SNA on the gene expression in psoriasis lesions. This information can establish the right formulation and dose of SNA for further research.
Primary Objective- To assess efficacy and pharmacodynamic effects of topical omiganan BID Secondary Objectives- To assess safety and tolerability of topical omiganan BID
The aim of the project is to study the effect of "CD11781/I, CD10394/101A and CD11406/B" on typical skin features of psoriasis. Thisinformation can establish the most effective compound, right formulation and dose for further clinical…
The aim of the project is to study the effect of "CD11891D, CD12681D, CD12455G and CD12446E" on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical…
Athlete*s foot is a contagious fungal infection affecting many people worldwide. This has led to the development of a self-care medical device for the treatment of athlete*s foot, which is effective, safe and easy to use in home care. Medical Brands…
The main objective is to evaluate the cytokine response to histamine iontophoresis in vivo, dynamically and non-invasively by means of transdermal analysis patches. The secondary objective is to correlate the cytokine response with morphological…
To investigate whether the upregulation of CK16 and Ki-67 (a marker for cell proliferation) in the FPSU is specific for HS, measured in inflammatory nodules and pseudo-comedones, in comparison to other dermatologic conditions that have comparable (…
The aim of the project is to study the effect of GRT on the synthesis and cytokine release in psoriasis lesions. This information can establish the right formulation and dose of GRT for further research.
The objective of this clinical trial is to assess the safety and performance of VIBLOK in adults with HSV-2 infection by comparing virus detection in the extra-genital area before and after application of the barrier cream.
Primary objective* To investigate the plasma pharmacokinetics of the first metabolite of dimethyl fumarate (DMF) - monomethyl fumarate (MMF) - following administration of the delayed- and slow-release FP187-GC tablet formulation after single dose…