39 results
Objectives: The primary objectives of the study are to assess whether 80 mg LY2439821 every 2 weeks (Q2W) or every 4 weeks (Q4W) is:* Superior to placebo at Week 12 in the treatment of patients with moderate-to-severe plaque Ps as measured by: o…
Primary Objective: Investigate whether early valganciclovir treatment of children with SNHL of >= 20 dB, unilateral or bilateral, and a confirmed congenital CMV infection can prevent deterioration of the hearing loss at 1 year follow-up.…
2.1 Primary study objectiveThe primary objective of this study is to investigate the therapeutic effect of an extensively hydrolyzed protein based infant formula with a synbiotic mixture on the severity of atopic dermatitis in infants.2.2 Secondary…
Evaluate long-term safety, tolerability and efficacy of adalimumab in subjects with moderate to severe hidradenitis suppurativa.
Finding an effective and permanent treatment against keloid.
1) Does FSAP activation in plasma of HAE patients contributes to bradykinin formation? 2) Study the inhibitory efficacy of c1-inhibitor towards kallikrein and FSAP towards bradykinin formation in a endothelial cell-based system. 3) test the efficacy…
Our primary objective is to visualize the vascular involvement in the pathogenesis of psoriasis with the TOPCam. In particular we asked the following questions:(i) Can the TOPCam image the structure of vascular changes in the clinical lesions?(ii)…
ln this study the effect of 1 novel compound on the development of psoriasis in the humanized mouse model isinvestigated. The efficacy is compared to a registered drug, Ustekinumab.
Primairy objective:- Evaluate the effect of bosentan on the blood flow in the hands from baseline to 12 weeks, measured by laser Doppler imaging, in SSc subjects with an early or active SSc pattern, measured with nailfold capillaroscopy (NFM), with…
Primary objective: to evaluate the efficacy of subcutaneous application of methotrexate in patients with moderate to severe Psoriasis compared to Placebo as assessed by achieving the primary endpoint PASI 75 after a 16 week treatment phase.…
Primary Objective:The primary objectives of the study are to demonstrate:• Superiority of LAS41008 versus placebo based on the proportion of subjects achievingPASI 75 at week 16 (a 75% reduction in the Psoriasis Area and Severity Index, PASI,…
The aim of the current proposal is to investigate the effects of changes in lifestyle, food intake, physical activity and health related behavior during adolescence on development of asthma, allergy and other chronic diseases. Health outcomes that…
The purpose of the present randomized controlled pilot study is to assess the efficacy, safety and practical aspects of autologous epidermal cell suspension grafting using ReCell in segmental vitiligo and piebaldism patients. Results of this study…
In this study, the efficacy of different type drugs, on the development of the psoriatic process in the humanized mouse model for psoriasis, will be evaluated. These different, registered drugs intervene at different levels of the psoriatic process…
The primary objective of this study is to determine the clinical safety and efficacy of adalimumab compared to placebo in subjects with moderate to severe HS after 12 weeks of treatment. A secondary objective is to evaluate safety and explore…
Primary objectiveTo compare the efficacy of subpurpuric pulsed dye laser treatment with different intervals between treatment sessions.Secondary objectiveTo evaluate the safety and the long-term effects of subpurpuric pulsed dye laser treatment.
To investigate the changes in facial- and hand analysis in patients with acromegaly as a result of medical treatment and pituitary surgery, and to investigate the changes in relational proportions between facial- and hand structures, incidence and…
The objective of the study is mapping and assessing of the effects of filaggrin mutation on atopic eczema and other atopic diseases together with serological parameters.
In the present study we sought to determine the levels of IL-1 cytokines in the SC and to relate them to FLG genotype, pH and the levels of filaggrin degradation products. Furthermore, we aim to investigate whether FLG genotype status relates to the…
ln this study the effect of 1 novel compound on the development of psoriasis in the humanized mouse model isinvestigated.