32 results
First, to explore relationships between immunological factors (cytokines and chemokines), psychological stress, and pain, controlled for infection. Second, to explore relationships between immunological factors (MBL), bacterial colonisation and…
To assess the effect of Caphosol® oral rinse on clinical outcomes of selected oral symptom burden (oral mucositis/stomatitis (aphthous-like), oral pain, taste change (dysgeusia), difficulty swallowing (dysphagia), difficulty oral intake, and dry…
A randomised controlled multcenter trial is performed to evaluate the perforator-based interposition plasty in comparison to full thichness grafts for scar contracture releases.
In this study the efficacy of a novel monoclonal antibody on the development of psoriasis in the humanized mouse model will be investigated.This experimental compound will be compared with 2 registered drugs, i.e. Humira en Stelara.
Analyses should indicate whether, in line with our hypotheses, CIM and CPM are improved after effective treatment in patients with chronic itch. When the hypotheses are supported, the study provides preliminary evidence for possible treatment…
To investigate the therapeutic effect of a selected probiotic mixture on the severity of AD in infants aged 0-15 months. The probiotic mixture has been studied in vitro and has proven IL-10 stimulating effects. Therefore it is thought to decrease AD…
The most important objective from this investigation is to prevent or substitute the damage which is coused by therapeutical radiation. As it's most likely that the skin damage as a result of therapeutical radiation can be more limited. From…
There are indications that early laser treatment of wounds can reduce scar formation. With the laser device the wound will be heated, which is thought to be responsible for a reduced inflammatory reaction and hence for a reduced scar formation. The…
This study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites. Results will help clinicians develop a standardized initial approach that prolongs survival and optimizes quality of…
Can a difference be measured in incidence of secondary wound infection after wound cleaning with either tap water or chlorhexidin?Hypothesis: After use of tap water in wound cleaning, no difference in incidence of secondary wound infection compared…
Assessing the value of SunshowerMedical Helios as a at home maintenance treatment for patients with psoriasis vulgaris.
Primary objective: 1. To evaluate the effect of ustekinumab in patients with moderate to severe hidradenitis suppurativa (Hurley II-III), measured by disease specific score systmes: Sartorius/HS-LASI and PGA 2. To evaluate possible changes in scores…
Primary* To monitor the occurrence of malignancy in pediatric subjects with extended oligoarticular JIA, ERA, or PsA.Secondary* To assess the long-term safety profile of etanercept.
The objective of the study is to assess the value of the *Topical Treatment Optimising Programme* in the topical treatment, which will be use together with the standard treatment, of insufficiently treated mild to moderate psoriasis after 8 weeks of…
To determine the effects of biphosphonates on radiation induced microvascular damage in the skin of breast cancer patients by comparing skin biopsies taken prior to and 4 months after treatment with a biphosphonate.
Correcting the causative factors of intertrigo is critical. Take steps to eliminate friction, heat, and maceration by keeping folds cool and dry. The goals of pharmacotherapy for intertrigo are to reduce morbidity and to prevent complications. To…
Primary Objective:* To determine the efficacy of silver impregnated dressings compared to a topical antibiotic to treat patients with PEG-site infections.Secondary Objectives:* To investigate the reduction and or change in stomal bacterial profile…
Determine the safety and efficacy of Tiscover compared to AS210 (acellular donor dermis, construct Tiscover is cultured on) for the treatment of chronic, therapy resistant (arterio-) veneus leg/foot ulcers in an out patient setting.
The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…
The objective of this study is to find out the relevance of adding isobornyl acrylate to the (meth) acrylate. Sub question: What is the relevant test concentration of isobornyl acrylate?