30 results
Research question:Does thin application of betamethasonvaleraat cream 0,1% on perniones lesions twice a day reduce the symptoms of patients as determined in 1st. line health care, with at least 10 mm expressed on a visual analogue scale, together…
What is the incremental cost effectiveness ratio of the use of etanercept versus infliximab?Are there subgroups of which infliximab or etanercept is more or less cost-effective in daily practice?Primary objectives: 1. To compare clinical efficacy of…
Primary Objective: To determine whether topical application of rapamycin can lead to reduction in size and/or number of fibrofolliculomas in BHD patients and may prevent the growth of new ones. Secondary Objectives: Safety, formula acceptability and…
Aim of this study is measuring the effects of locoregional anaesthesia in EDS patients and comparing these effects with those in a healthy control group. The results of this study can be used to make a more valid choice for the type of anaesthesia…
Primary Objective: To show superiority of the novel fixtures compared to standard fixtures regarding stability of the implants measured as ISQ values.Secondary Objectives: 1. To compare the long time survival of the standard fixtures and abutments…
ACT reduces the incidence of PTS after DVT. In the Dutch CBO-guidelines current therapy is adviced for 2 years after diagnosis because most PTS develops within 2 years after DVT, with a peak incidence in the first year.Some clinicians claim that one…
The objective is to assess the effect of adalimumab on selfconfidence and sexuality of patients with anogenital psoriasis.
To assess the efficacy of treatment with monochloroacetic compared to treatment with cryotherapy regarding patients with handwarts and compared to combination therapy (salicylic acid and cryotherapy) regarding patients with plantar warts.WARTS-1 has…
The objective of this retrospective study is to compare the outcome of the different treatment options(surgical or non-surgical) for fingertip injury.
The comparison of numbers and suppressive function of Treg in a population of severe psoriatic patients in peripheral blood by flowcytometry and the assessment of a Th17 (e.g. IL-17) cytokine profile from the supernatants. Furthermore, the relation…
We expect faster clearance of psoriatic lesions with the use of short-contact, local tar application during UVB-therapy, which will result in a lower cumulative UVB dosage.
Is topical application of compound Z effective in reducing the development of psoriasis, induced in this humanized mouse model?
With this study we want to validate the negative pressure instrument which can make suction blisters, so in the future it can be used for other purposes. It can be helpfull to study the effects of medication or other treatments on blister formation…
To test whether the anatomical success rate of Steam Ablation is not inferior to that of EVLA in treatment of GSV insufficiency and compare the treatment related complications, patient reported outcomes and cost-effectiveness analyses between EVLA…
To estimate the one year-prevalence of contact allergy to fragrance ingredients in the general population of six different geographical areas in Europe spread over five different countries
Primary Objective: 1) We want to investigate whether carriers of FLG-null mutations show higher responses to exposure to the skin irritant SLS than non-carriers.2) Furthermore, we want to investigate whether carriers of mutations in the genes coding…
To assess quality of life in patients who underwent an amputation because of serious CRPS-*, with life threatening ulcers or infections, or unbearable and therapy resistant pain in a none functional limb that had a negative influence on the…
Primary objectives: (1) Evaluation of the efficacy of vaccination against HPV 16, 18, 6 and 11 followed by local applications of imiquimod 5% cream compared to treatment with imiquimod alone for usual type VIN, (2) evaluation of the systemic and…
The objective of this study is to obtain whole blood from patients with S. aureus infections and/or patients whose wounds are colonized by S. aureus for in vitro development of human monoclonal antibodies against S. aureus.
To compare the efficacy and safety of methotrexate versus azathioprine treatment in adult patients with chronic severe AD.