21 results
1) To determine the prevalence and the sensitivity for various antibiotics of Staphylococcus aureus in the nose (carrier) of patients visiting the outpatient department of Dermatology.2) To determine the prevalence and the sensitivity for various…
Primary objective: to prove or exclude an association between the amount of TFG-*3 in the blood and the development of HTS and keloid.Secundary objectives:- to research the association between collagen composition of the skin and the POSAS score;-…
Transmural care for hand eczema. A randomized controlled trial with an economic evaluation alongside
1) To develop and implement a protocol for transmural, multidiscplinary care for hand eczema, coordianted by a case-manager.2) To evaluate the (cost)effectiveness of the multidisciplinary protocol for transmural care in hand eczema
Proof that laser treatment will be better than the routine method using curettage. Besides it is claimed that laser treatment is less painfull.This will be assessed by photography, in which only black white (grey) evaluations are made. Colours are…
The primary objective of this study is to compare the efficacy of wet wrap therapy with diluted corticosteroids versus wet wrap therapy with emollients. The secondary objective is to develop an effective and objective value for monitoring the…
The aim of the extended follow-up of the PIAMA cohort is: To investigate changes during the ages of 8 to 11-12 years in lifestyle, nutrition, physical activity and health related attitude and behavior that are relevant to the development of asthma,…
The target of this study is to determine if blue light of 420 nm is effective against psoriasis
A randomised controlled trial is performed to evaluate the clinical effectiveness of the skin stretching technique for two categories:a. acute burn wounds: wound closure by means of skin stretching should lead to a significant reduction of scar…
Objectives:To assess the safety of transitioning subjects to Raptiva therapy from standard oral systemic or phototherapy by overlapping with Raptiva whilst tapering the initial systemic therapy or phototherapy dose. The secondary objective is to…
The objective of this study is to evaluate the difference in clinical effects (onset and degree of repigmentation) of NB-UVB and fluticasone proprionate vs NB-UVB alone.
Primary objectives:• To explore whether daily oral treatment with 30 mg prednisolone modulates biomarkers for adverse metabolic effects in a similar manner in patients with chronic atopic dermatitis as compared to healthy volunteers.• To determine…
Primary Objective: What is the frequency of positive patch test reactions to the 26 declarable fragrance allergens in fragrance mix I and/or II positive participants?Secondary Objectives: Do Weleda cosmetic products containing essential oils,…
To find out the dynamics of cell biological changes in lesional skin during treatment with adalimumab. Secondary objectives:- To find out whether adalimumab treatment results in (1) a reduction of T cell subsets, (2) normalization of proliferation…
Investigate the role of CD8+ T cells in AD by:a. Isolation of T cells from the skin and determination of the percentage and phenotype of CD8+ T cells in both acute and chronic AD, using the APT as an in vivo induction model. Comparison with…
To assess the long-term safety, tolerability and efficacy of ABT-874 in adults who have either completed or have demonstrated a loss of response (as defined in the original ABT-874 protocol) to treatment in a preceding ABT-874 study in the treatment…
Aim of the studyIn addition to the aims of the compassionate use protocol.To study:1. hypothalamic structure before and during leptin therapy2. hypothalamic function before and during leptin therapy
The primary objective of this study is to compare the effectiveness of two different phototherapy protocols (continuous treatment for 6 months, or 2 continuous treatments for 2 months separated by one month interruption (2-1-2-1), with a total…
The primary goal is investigating the number of women that have lymphedema five years after the treatment for breast cancer. In the describing part of this study, the focus will be on the correlation between lymphedema and 1) surgical treatment, 2)…
Overall aim: To study the influence of M.leprae antigens on differentiation and maturation of DCs and to identify M.leprae antigens, receptors on antigen presenting cells and signaling pathways which play a role in leprosy pathology. Main objective…
The aim of this study is to develop and validate the basophil activation test by flow cytometry in our hospital as an extra diagnostic procedure for patients, who can not be diagnosed with existing tests or who have the risk of developing…