415 results
The objective of the study is to assess the feasibility and diagnostic yield of OCT guided thrombus aspiration in patients presenting with initial conservative management of non-ST-elevation myocardial infarction (NSTEMI).
In the current study, we want to determine and correlate the results of both perfusion capacity (with MR imaging) and sublingual glycocalyx dimensions in a) patients with proven obstructive coronary artery disease and b) patients with angina but…
The objective of this study is to assess changes in lung aeration and lung perfusion in patients who will undergo electrocardioversion.
Fontan circulation: Analysis of its Impact on quality of life and Rate of deterioration (FAIR study)
Primary Objective: - Investigating the rate of the attrition and predictors of the failing Fontan circulation, defined as decrease in functional capacity. Secondary Objective(s): - Investigating predictors of decrease in NYHA class of Fontan…
The objective of this study is to determine the effectiveness of the CHA2DS2-VASc prediction model as directive for the preventive management of AF patients in the first line.
We hypothesised that cardiovascular changes already exist in children with cystic fibrosis compared with healthy control children. Therefore, we will evaluate the cardiovascular system in a group of children with cystic fibrosis compared with…
Objective: To determine the (added) value of molecular imaging techniques for selecting patients that will benefit from CRT.
AKINESIS is a multi-center prospective, uncontrolled clinical study to assess the utility of a plasma NGAL test (Triage® NGAL Test) and a urinary NGAL test (ARCHITECT® Urine NGAL) in predicting worsening renal function in patients presenting with…
Determining the optimum moment of 123-Iodine meta-iodobenzylguanidine (MIBG) myocardial scintigraphy
The purpose of this study is to investigate whether H/M ratios from late scans, performed earlier than 4 hours post-injection of MIBG, are comparable with those determined at 4 hours
Primary Objective: With this study we aim to cross-culturally validate the SQUASH questionnaire (self-reported habitual physical activity) using an independent, objective measurement of physical activity, i.e. an Actiheart device (heart rate and…
Is sympathetic innervation and perfusion disturbed in patients with chronic kidney disease and will is change after HD?
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
- To investigate the cause of the symptoms patients with a vagus nerve stimulator experience during exercise.- To investigate whether there are changes in EEG during stimulation.
Primary Objective:• To investigate the relationship between ID, VB12D or FD and outcome (HF hospitalization and all-cause mortality) in patients with chronic HF. Secondary Objectives:• To investigate the prevalence of ID, VB12D or FD in chronic HF…
* To establish the feasibility (i.e. % of measurements with sufficient quality for analysis) of exercise echocardiography in CHF patients, focusing on left ventricular function (LVEF), myocardial tissue motion (intra- and interventricular…
The objective of the study is to demonstrate that the creation of cardiac lesions with epicardially applied RF ablation through a minimally invasive surgical (MIS) approach plus EP ablation performed when needed at least 3 months later enhances the…
The purpose of the GLOBAL study is to perform whole-genome genotyping, next-generation deep resequencing, gene expression profiling, metabolomics, lipidomics and proteomics of atherosclerosis in patients phenotyped using advanced CT-based imaging…
To identify the influence of two different biocompatible-coated extracorporeal circuits on the perfused boundary region of the sublingual microvasculature as measured by the GlycoCheck Sidestream Darkfield Imaging camera.
To determine the (added) value of molecular imaging parameters for selecting patients that will benefit from CRT, specifically:-Phase standarddeviation-Summed infarct score-Innervation Heart/Mediastinum ratio