109 results
- To determine physical fitness in children with a congenital heart disease (ventricular septum defect, atrium septum defect, tetralogy of Fallot, transposition of large arteries and patients after a (modified) Fontan-operation) and to compare…
BAY 63 2521 is a direct stimulator of the soluble Guanylate Cyclase (sGC) and is intended for the treatment of cardiovascular diseases, especially Pulmonary Hypertension (PH).To assess the efficacy and safety of oral BAY 63 2521 in the treatment of…
The study will assess the hypothesis that the combination warfarin & clopidogrel 75 mg/day is superior to triple therapy (warfarin + clopidogrel 75mg/day + aspirin 80mg/day) with respect to bleeding complications while equally safe with…
Is sympathetic innervation and perfusion disturbed in patients with chronic kidney disease and will is change after HD?
BAY 63 2521 is a stimulator of the soluble guanylate cyclase (sGC) and is intended for the treatment of cardiovascular diseases, especially pulmonary hypertension (PH).To assess the longterm safety and tolerability of oral BAY 63-2521 in patients…
BAY 63 2521 is a stimulator of the soluble guanylate cyclase (sGC) and is intended for the treatment of cardiovascular diseases, especially pulmonary hypertension (PH).To assess the efficacy and safety of oral BAY 63 2521 in patients with inoperable…
The trial will test the hypothesis that ICD implantation without defibrillation testing (DT) is non-inferior to implantation with testing against the composite endpoint of ineffective first appropriate clinical shock or arrhythmic death.
To determine the add-on value of bi-atrial pacing in combination with standardised Sotalol treatment for the prevention of postoperative atrial fibrillation (POAF).
At CHDR, experience has been gained with the assessment of the in vitro inhibition by MAP kinases of the LPS-induced TNFα release in healthy male volunteers. However, relatively little is known on the inhibition by MAP-kinases in other populations.…
The present study is designed to test the hypothesis that new imaging modalities like PET with the use of HED and contrast enhanced CMR to quantify fibrosis size and heterogeneity of scar tissue can give a further risk stratification for ventricular…
To demonstrate whether using MSCT to reclassify individuals who are at high-risk based on traditional risk factors.
see separate synopsis
Can mobile echocardiographic and pulmonary function measurements be performed adequately and patient-friendly within 24 hours after admission to hospital and before discharge in COPD patients aged 65 years or over with an exacerbation?
to investigate the risk of death and incident cardiovascular diseaseto investigate the risk of mild cognitive impairment and incident (vascular) dementia
1. To detrrmine the applicability of standard energy expenditure prediction equations for accelerometry in measuring physical activity in children with musculoskeletal and other chronic diseases (see below).2. To develop disease specific prediction…
The aim of the proposed study is to examine whether CRT has a positive effect on microvascular function and health outcomes, and whether psychological factors may moderate the effect of CRT on health outcomes.
The primary objective of this study is to develop a short and feasible screening package which is specific and sensitive to detect psychosocial problems in patients with CD.
The main objective of this study is to investigate the relation between Cx40 polymorphism and protein expression in the general population and patients without a history of AF.
1) To assess whether a correlation exist between the degree of pulmonary clearance of free radical positive white bloodcells and platelets and the degree of pulmonary congestion in congestive heart failure (CHF) patients2) To asses whether cardiac…
Evaluation of the long term results of surgical carotid denervation in patients suffering from CSS.Primary question:Is surgical denervation an effective treatment option for symptoms caused by CSS, eg dizziness and syncope, on the long term.…