52 results
To study the effects of transient severe endogenous stress hormone exposure on the structure and functioning of brains circuitry regulating emotion, and the association with cognition and psychopathological symptoms.
To describe the differences in macrophage infiltration and mRNA expression of adipocytokines in subcutaneous, omental and perirenal fat tissue in Cushing's syndrome compared to healthy controls.
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
We hypothesize that cardiovascular risk factors may already be present during childhood in CAH patients. Therefore, we will perform a cross-sectional study in CAH patients aged 1-16 years evaluating blood pressure, lipid profile, insulin sensitivity…
The aim of our study is to investigate whether PTH levels measured between 4-24 hours after surgery can accurately identify patients with permanent hypoparathyroidism after thyroid surgery who need long-term calcium supplementation.
Primary objectives is: - To evaluate the effects of dehydration (fluid deficit) on coagulation and fibrinolytic parametersSecondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to dehydration is…
Primary objective is: - To evaluate the effects of dehydration and subsequent rehydration on coagulation and fibrinolytic parametersSecondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to fluid…
To study HPA axis regulation and sympathetic nervous system activity in survivors of childhood ALL during relaxation and during stress.
The primary objective of this study is to assess the relation between the short term metabolic changes after start of rhGH therapy and the long term change in height SDS after one year of treatment. Secondly, we want to assess the effects of GH on…
Our goal is to evaluate if this onsite assessment and aspiration during punction reduces inadequacy of specimens and see if onsite assessment by the aspirator is performed accurately after a brief instruction by a cytopathologist. Primary Objective…
To answer the following research questions:How is quality of life in patients with adrenal insufficiency?How is cognitive functioning in patients with adrenal insufficiency?Is there a difference in cognitive functioning between patients who did/did…
Main objectiveTo describe the experienced pain sensations of temperature and to describe the different temperature sensitivity thresholds using Quantitative Sensory Test (QST) in the different patient groups.secondairy objectiveAs a measure of the…
The objectives of this pilot study are to explore differences in sleep and fatigue, and the relation with the function of the HPA axis, between survivors of childhood ALL and healthy controls.
Primary objective is: - To evaluate the effects of (controlled) dehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to dehydration is mediated…
Primary objective is: - To evaluate the effects of dehydration and subsequent rehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to fluid…
To document cardiac function before and after treatment of CS.
a. analysis of the usefulness of new molecular biological techniques in the diagnostic process of short stature, especially the detection of small chromosomal anomalies.b. identification of genetic factors causing short stature or influencing the…
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To collect data regarding the prevalence of:I) - osteoporosis in SCI patients and the relation to characteristics of SCI. - fractures in SCI patients and the relation to characteristics of SCI. - active treatment of osteoporosis in SCI patients.II…
To investigate the correlation between androstenedion in saliva and serum in all patients that have a request for androstenedion in serum.To collect age related reference ranges for healthy children on three different time points.