614 results
Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…
Clinical, prospective, non-randomized trialOrbis Medsich Centre, Sittard-Geleen
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
The aim of this study is to test the hypothesis that a gentamicin-collagen sponge reduces the incidence of surgical site infection (SSI) in patients undergoing inguinal dissection for vascular disease
To measure the wavelength dependent differences in optical properties between normal and malignant breast tissue over a broad wavelength range (400-1000 nm).
To study the relationship between (a) abnormal concentrations of plasma amino-acids, pterins, HVA and inflammatory parameters and (b) the severity, duration and outcome of delirium. To find a biochemical profile that predicts the occurrence of a…
Comparison of preoperative diets before bariatric surgery with a randomized non-inferiority trial in order to compare the standard VLCD with a standard diet.
The overall aim of the present study is to identify the determinants of (recurrent) falls before and after orthopaedic surgery, either due to fall-related injuries or to lower limb joint replacements, in subpopulations of older orthopaedic patients…
With this pilot study we aim to prove that our optical spectroscopy system can provide accurate identification of nerve tissue during surgery.
1) To investigate what changes are present in skeletal muscle tissue of elderly gastric and colonic cancer patients (>80) compared with younger gastric and colonic cancer patients (<60) and compared to elderly controls and younger…
In this sub-study we want to unravel the exact mechanism and provide more information about the efficacy of the BaroSense ACE* Stapler. Therefore we will measure changes in various parameters that are known to affect weight loss and metabolism,…
The primary objective is to examine the predictive value of several types of endogenous inhibitory functions for the risk and severity of acute and persistent pain after surgery. As primary outcome parameter, patients will be asked to keep a pain…
Objective: The primary objective is to evaluate whether distal LRYGB (DLRYGB) is superior in terms of %EWL after one year follow-up compared to standard LRYGB (LRYGB). Secondary objectives are to evaluate effect on quality-of-life (QOL), cure /…
The primary aim of this research project is to investigate the prevalence and bother of OAB before and after POP repair surgery and to determine changes in bladder function after surgery. Secondary aim is to identify predictors of persistence,…
The primary objective of this study is to assess whether *omics technologies are sensitive and specific enough to be used as a chemical risk assessment tool for humans. More specifically the study will demonstrate if there are different and / or…
primary objective:-to define the optimal glucose intake by quantifying endogenous glucose production and fractional gluconeogenesis in critically ill children.secundary objectives:-determine glucose utilization in relation with exogenous glucose…
Objective of this research is to evaluate whether neo-adjuvant chemo-/radiotherapy in small non-advanced rectal cancers can be used to obtain a complete or near complete remission. In these patients could a complete resection of the rectum as an…
Assessing the effectiveness and safety of parecoxib compared to placebo in pain relief children undergoing scoliosis surgery
In the Netherlands, gum chewing has not been incorporated in the standard postoperative care after intra-abdominal surgery. Therefore a multi-center RCT was set up to evaluate the influence of gum chewing on the development of ileus. Our null…