269 results
To evaluate the blood pressure within the first year of life we will perform a prospective longitudinal study in all newborn patients with the classical form of CAH. To analyze the urinary steroid profile in CAH patients and healthy controls during…
Primary Objective: To determine the accumulation of AGEs in the skin and serum of pregnant women with DM1, DM2 or GDM, in comparison to healthy pregnant women and non-pregnant women with DM1 or DM2 and to determine the accumulation of AGEs in the…
To see if the new drug can prevent development of psoriatic changes in the transplant model of psoriasis
To compare the efficacy of playing Tetris to Assessments Only in the reduction of frequency, vividness, and emotional intensity of intrusions in Dutch soldiers exposed to aversive events on deployment in Afghanistan.
The relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients.
The primary objective of this study is to examine the relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients in the Forensic Psychiatric Center Dr. S. van Mesdag in Groningen. In addition to this,…
In this study we aim to validate changes in the pulse pressure after controlled volume loss during blood donation in spontaneously breathing subjects. This validation will contribute to the development of a standardized manner in which the Nexfin…
The primary objective of this study is to examine the difference in VOC pattern of exhaled air (breathprint) between patients with histology-confirmed diagnosis of colorectal cancer and healthy controls. The secondary objectives are to investigate:…
The main objective is to study precision control of trunk posture and associated muscle recruitment in LBP patients and healthy controls during trunk positioning tasks in which postural control is challenged, by increased dead space breathing, by…
The objective of the study is to observe the effect of olanzapineat a dose of 10 mg daily for 14 days when given with/without topiramaat at a dose of 25 and 50 mg twice daily on bodyweight in healthy male subjects. In addition the effect of…
Primary:- to evaluate the safety and tolerability of the compound in different multiple dosing regimens in healthy subjects in different dosing regimensSecondary:- to characterize the pharmacokinetics of multiple oral doses of LY2878735 administered…
Primary:Part I:- to determine the effects of gabapentin and remifentanil on the evoked area of hyperalgesia, area of allodynia, pinprick hyperalgesia and background pain using a newly developed HCW sensitization modelPart II: - to determine…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…
Primary objective:The main aim of the current study is to identify novel pathophysiological pathways associated with the development of post-MI HF using genome-wide data and innovative bioinformatics approaches. Specific aims1) Identifying and…
The aim of this study is to investigate whether weeklong dietary intake of estrogens via high cow*s milk consumption in the Dutch population increases systemic estrogen concentrations. To this aim, estrogen levels are measured in urine samples of…
The aim of the project is to evaluate the best method of supported care in general practice that leads to greater self-sufficiency, higher retention of functions and thus improved quality of life, less use of care facilities and a lower burden of…
Optimize the protocol for linear amplification of tumour RNA extracted from FNA's under GMP conditions.
Primary Objective:To assess the ability of BR55 to identify area(s) of VEGFR2 expression in human prostate by ultrasound molecular imaging on the basis of a visual score in comparison with histopathology analysis (location based on expression of…
Primary Objective: To answer the following question: Does the extended approach (defined as uroflowmetry and bladder scan after the first consultation, followed by a check-up in month 3 of the male patient over 50 years of age first presenting with…
Objective is to determine the stump volume change in lower limb amputees, in the post operative period. Especially interesting is to know when the stump volume stabilizes, and doesn*t decrease anymore, and if there are any fluctuations in volume.