3 results
Approved WMOCompleted
- To evaluate the safety and tolerability of ascending single oral doses of ACT-462206 in healthy male subjects.- To investigate the single oral dose PK and PD of ACT-462206 in healthy male subjects.- To investigate dose proportionality across…
Approved WMOCompleted
The purpose of this study is to determine the effect of JNJ-64251330 in participants with Familial Adenomatous Polyposis(FAP) on colorectal polyp burden (sum of the polyp diameters).
Approved WMORecruiting
Cohort ATo compare the CRR for the combination of pembrolizumab + BCG versus BCG alone in participants with CIS.Cohort B- To compare the EFS between participants who receive pembrolizumab + BCG (reduced maintenance) versus BCG alone- To compare the…