1843 results
In 2009, a new combination of MRI sequences was published by Deoni et al. (2009) that promised the ability to measure the myelin water in vivo over the whole head in a clinically useful time. Referred to as mcDespot (multi-component driven…
The objective of the present study is to investigate the course of psychosocial functioning in stroke patients and their partners, during the first 2 years post-stroke, to investigate factors predicting psychosocial functioning in stroke patients…
The aim of our studies is to explain weight gain in individuals based on their geneticpredisposition, and their physiological and behavioral responses to the current obesogenicenvironment and to define personality subtypes, which specify the…
The NEURONED-MS cohort study aims to facilitate prospective observational research in the field of multiple sclerosis (MS). This cohort will serve as the central part of several projects that will be organized to address various issues including:1.…
Our aim is to make ROM suitable for patients of Moroccan or Turkish origin. In order to achieve this, necessary steps need to be taken: (1) translate and cross cultural adapt ROM questionnaires; (2) validate the translated questionnaires; and (3)…
RESEARCH QUESTIONS* Is the currently used RNAF protocol for the acute medical care on the Battlefield sufficient.* What recommendation can be made to enhance this protocol, with emphasis on the transfer of information from battle field to second…
Primary: to develop and validate a clinical prediction rule to predict a favourable or unfavourable disease course for NP patients, therewith enabling tailor made treatments for NP patients.Secondary: determine prevalence of clinical signs of NP in…
The main aim of this implementation research is to systematically screen all RA patients of Reade rheumatology and revalidation centre in Amsterdam for their cardiovascular risk profile and if necessary to treat them for cardiovascular risk factors…
1. To determine the reproducibility of the ECWT and the 6MWT to assess the physical strain of walking in patients with PPS and in healthy control subjects.2. To evaluate the one-year course of the physical strain of walking among patients with PPS…
To determinate the efficacy and safety of golimumab in patients with ankylosing spondylitis in daily clinical practice prospectively. In addition, the effect of treatment with golimumab on the lipid profile will be monitored during this study.
Actualize, replicate and extend the data of NEMESIS-1 with regard to the prevalence, incidence, course and consequences (functioning, mental health care use and costs) of psychiatric disorders among the general population of the Netherlands.…
A fundamental question in the current research proposal concerns how changes in cognitive and social-emotional behavior are related to functional and anatomical brain development. The current proposal has the objective to (a) understand the neural…
To relate exposure markers of EDCs to health outcomes in children - in particular obesity and neurobehavioral disorders -, effect biomarkers, and other parameters via multiple regression and multivariate analysis, while taking into account relevant…
To demonstrate differences in neuronal structure and neuronal function in brain regions that control eating behaviour between obese and normal weight adolescents.
1) to investigate cognitive functioning in lacunar infarct patients with and without periventricular white matter lesions; 2) to identify predictors for cognitive dysfunction in lacunar infarct patients.
To investigate the dynamics of tumour hypoxia as assessed by 18F-FAZA PET/CT during and after chemoradiotherapy. To investigate the best strategy to deliver a boost dose to the hypoxic tumour areas. This strategy may be either a simultaneous boost (…
The aim of this study is to objectively and subjectively characterise different aspects of oral function for malignancy of the oral cavity.
Developing a risk score based on established risk factors and personality traits, to predict possible postnatal anxiety/depression with or without problems in bonding between mother and child at the first consult at the midwives practice or…
Objective of the study is to quantify the microbiological etiology in immunocompromised patients, at least 18 years of age, with CAP needing hospitalization. And to determine the severity, antibiotic use and outcome of CAP in immunocompromised…
The primary objective for this study is to compare the level and time course of the patient work-of-breathing during PS ventilation with the work-of-breathing during SIMV-PS ventilation with a lower rate of breaths per minute delivered by the…