3231 results
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…
We hypothesize that the T2T strategy is superior compared to the T2S in retaining gout remission and is also more cost-effective.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
We hypothesize (based on literature) that the incidence of chronic pain in The Netherlands is around 15-20% in patients presenting to the emergency department with (acute) pain related complaints. We have no further hypothesis, because of the…
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
We hypothesize that patients with a HER2-negative primary tumor but with at least one HER2-positive CTC benefit from HER2 targeted treatment with trastuzumab
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
During the pandemic wave the immunity against COVID-19 will build up across the different age groups in The Netherlands.
To assess the prevalence of LDL-C >1.8 mMol/L in a subgroup of very high risk patients with ASCVD, who remain at a very high-residual risk for ACS, despite treatment with high-intensity statins in combination with ezetimibe. This subgroup of…
The aim of our descriptive study was to quantify the disease burden leading to hospital-based care, repatriation or death in Dutch travelers during their stay in a foreign country, including Europe. The outcome of this study could be used as…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
Effective postoperative pain control is an essential and humanitarian need of every surgical procedure. Inadequate pain control may result in increased mortality, delayed recovery and increased hospital costs (1). The optimal perioperative analgesic…
Obtain insight into the (difference in) pertussis-specific immunoglobulin G (IgG) levels in the first three months of life between infants whose mothers received a pertussis vaccine (Boostrix) during pregnancy in comparison to infants whose mothers…
At the primary end-point (12 months), the clinical effectiveness of physiotherapist-led exercise therapy is hypothesized to be significantly greater than a corticosteroïd injection. With anticipated greater positive effects on work absence (largest…
Primary Objective: 1. What is the difference in effectiveness of Early Time-restricted Eating (eTRE) in glycaemic regulation when compared to isocaloric continues caloric restriction (CCR) after one year in overweight adults with type 2 diabetes?…
"The main objective of this trial is to assess long-term performance and obtain real-world experience with the bi-hormonal fully closed loop system (Inreda AP®)"
"Objective: The primary objective is to evaluate if %EWL after LSG as bariatric therapy is equal or, within an acceptable margin, inferior to LRYGB. Secondary objectives are to evaluate QOL, cure /improvement of obesity related co-morbidity (i.…
We hypothesize that telemonitoring through SpA-Net, in combination with patient-initiated care, will lead to less outpatient visits, without compromising quality of care and health outcomes. Furthermore, we expect that telemonitoring through SpA-Net…
Our primary objective is to compare the effectiveness of NACD and ESWT for patients with calcifying tendinitis of the shoulder. Our hypothesis is superiority of NACD or ESWT above the other treatment in functional recovery over a period of 12 months…
To determine the content validity and clinical utility of the Dutch sPCI according to nurses with expertise in stroke care and stroke patients, respectively.