24 results
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
The objective of the study has the intention to prove that a pre-and dysmature baby in a supported back-position, by the use of a controlled moulder, shows more signs of comfort than a specific baby in a freely supine position.We are basing…
The main objective of this proposal is to request permission for recruitment and participation of individuals between ages 8 and 30 in an fMRI session and several behavioral testing sessions. These studies are aimed at relating brain development to…
To assess the long-term effects of in utero exposure to progesterone or a pessary on child (neuro)development and behaviour at 6 years of corrected age
To describe and investigate safety and tolerability of the intradermal delivery of two fractional doses of 20 µg mRNA-1273 in patients with Fibrodysplasia Ossificans Progressiva.To compare the immunogenicity of patients with FOP after intradermal…
The present study aims to address the limitations of earlier research, by employing a large sample size, and investigating the possibility that music therapy has an effect on wellbeing of people with dementia when using blinded outcome assessments…
1. To test the hypothesis that an age adapted immunosuppressive regimen targeted at reduced immunosuppression with low calcineurin inhibitor exposure will result in improved outcome in elderly recipients of A: kidneys from older deceased donors (…
The assumptions of the traumatic effects of coercive measures as described in the literature will be examined in the present study. The research questions are how coercive measures are experienced by patients, to what extent these measures are…
In the future, the determination of CTCs and ctDNA in the CSF could be a new quantitative method for the anti-tumor response assessment of systemic or intrathecal therapy (as opposed to CSF cytology, which is subjective and not a quantitative method…
To evaluate the efficacy of low molecular weight heparin (LMWH) in women with inherited thrombophilia and recurrent miscarriage on live birth.
- International network among European (125 cases) and Iranian (125 cases) centers- Prospective enrollment of the 250 VWD3 patients using a common database online- Detailed information about previous bleedings and exposure to VWF concentrates-…
Objective of the study is to evaluate whether parameters can be identified that predict which graft ultimately prevails following cord blood transplantation after a reduced intensity conditioning regimen in adult patients .In addition engraftment,…
Primary objectiveTo investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancraticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall…
The purpose of this study is to investigate the acute hemodynamic effects of restoration of AV coupling by atrio-biventricular pacing in patients with HF and prolonged PR interval.
To determine whether fluorescence imaging using ICG for the assessment of DIEP flap perfusion during surgery decreases the occurrence of fat necrosis compared to standard intraoperative clinical assessment of DIEP flap perfusion.
1) To study cognition in children with absence epilepsy and the development of functional brain organization.2) To find prognostic factors in terms of clinical, 24h-video-EEG or/and MRI characteristics for cognitive deterioration and/or poor seizure…
Primary Objective: to show a reduction in eGFR decline in patients treated with LCP tacrolimus compared to IR tacrolimus. Secondary objectives will include investigating the potential decline in other known side effects of calcineurin inhibitors i.e…
In patients with severe asthma and high eosinophil counts (>=250 cells/µl) receiving SoC asthma therapy, to demonstrate the efficacy (as measuredby rate of moderate-to-severe asthma exacerbations) of at least one dose level of QAW039 (150 mg…
The primary objective of this trial is to investigate the effects of probiotics, as compared to placebo, when given in addition to antipsychotic/mood stabilizing medication to a selected patient sample. Our aim will be to lower symptom severity as…
The goal of this study is to visualize and quantify the somatostatin receptor expression and occupancy directly before and after the injection of long-acting lanreotide in NET patients by imaging with [68Ga]-DOTATATE PET.