15 results
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
Primary objectiveTo evaluate if tralokinumab after 14 weeks of treatment (at steady state) changes the metabolism of substrates of CYP 1A2, 2C9, 2C19, 2D6, or 3A4 pathways in subjects with moderate-tosevere atopic dermatitisSecondary objectivesTo…
This study aims to examine the effects of different manners in which counselors communicate uncertainty and respond to counselees* uncertainty, on analogue patients* affective and cognitive outcomes. In addition, the results of this study are used…
The present study aims to address the limitations of earlier research, by employing a large sample size, and investigating the possibility that music therapy has an effect on wellbeing of people with dementia when using blinded outcome assessments…
Neurotransmitter systems, such as dopamine, are influenced by sex hormones (Riccardi et al., 2011); in fact, with respect to sex differences in dopaminergic neurotransmission, it has been suggested that in dopamine regulating genes, sexual…
The WIDE project aims to investigate if implementation of WGS in molecular diagnostics is feasible in routine practice at the Netherlands Cancer Institute (NKI).
The aim of the study is to test whether the implementation of a package of specific measures during the night shifts at the emergency room, alertness and performance during the night, sleep and physical complaints in general change.In addition, we…
The Role of microbial produced ethanol in etiology of Non-Alcoholic Steatohepatitis (ETHANASH trial)
To investigate whether microbial produced ethanol plays a role in the development of NASH.
1. To test the hypothesis that an age adapted immunosuppressive regimen targeted at reduced immunosuppression with low calcineurin inhibitor exposure will result in improved outcome in elderly recipients of A: kidneys from older deceased donors (…
To assess the feasibility and safety of bronchoscopic/endosonography guided needle based confocal laser endomicroscopy patients with suspected or proven lung tumor and/or mediastinal/hilar lymph node metastases
To assess the effect of a Roux-en-Y gastric bypass on the pharmacokinetics of a single oral dose of 1000 mg paracetamol
To examine the efficacy of targeting atrial fibrotic tissue during an ablation procedure in treating persistent AF.We will also examine the efficacy of the fibrosis-guided ablation on a number of secondary or exploratory outcomes including the…
Primary Objective: to show a reduction in eGFR decline in patients treated with LCP tacrolimus compared to IR tacrolimus. Secondary objectives will include investigating the potential decline in other known side effects of calcineurin inhibitors i.e…
1) To study cognition in children with absence epilepsy and the development of functional brain organization.2) To find prognostic factors in terms of clinical, 24h-video-EEG or/and MRI characteristics for cognitive deterioration and/or poor seizure…
To determine if emixustat hydrochloride (emixustat) reduces the rate of progression of macular atrophy (MA) compared to placebo in subjects with Stargardt disease (STGD)1. To evaluate the safety and tolerability of emixustat compared to placebo2. To…