293 results
Intranasal administration of cobalamin can be used as an alternative for the standard intramuscular injection of cobalamin in cobalamin deficient patients.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
Our hypothesis is that adolescents that have been educated on an 'enjoy being fit' elementary school exhibit healthier scores than adolescents that have been educated on a regular Elementary school on the set of outcome variables. However…
Patients with ADAM12 > 203 ng/mL in their serum benefit from the addition of biweekly tocilizumab for 3 doses to neoadjuvant chemoradiation before esophagectomy
We hypothesize that peripheral perfusion targeted fluid management (PPTFM) might prevent excessive fluid administration, leading to less formation of tissue edema, less respiratory dysfunction and shorter duration of mechanical ventilation.
An intervention consisting of a set of specific fatigue reducing and health enhancing advices will lead to less fatigue and sickness absence in airline pilots. Following the intervention and the accompanying advices will lead to pilots reporting…
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
We anticipate that students who will receive the Internet-based intervention based on their symptoms will have high satisfaction and show high adherence to the program. We also expect to find significant improvements in symptoms of stress /mood and…
We expect an increased bone mineral density in the calcar region compared to the other ROI’s. Furthermore, we expect early detection of decreased mineral density of the femoral head in patients developing osteonecrosis of the femoral head.
We hypothesize that providing feedback to hospitals will reduce practice variation
Drug-induced Sleep Endoscopy with cocomittant jaw thrust maneuver is a suitable predictor for succes of oral appliance treatment.
The aim of this study is to investigate the non-inferiority of perioperative continuation of aspirin patients undergoing spinal surgery, compared with the current policy of perioperative discontinuation of aspirin.
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
1. Women who receive early intervention EMDR will have less PTSD (symptoms) than those allocated in the care-as-usual group. 2. Early intervention EMDR will have a positive effect on Quality of Life, Fear of Childbirth, depressive symptoms, mother-…
Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma
We hypothesize that the number of patients without vertigo spells at 12 months follow up will be higher in the group that has undergone EDB than in the decompression group.