388 results
A model based on the combination of clinical prognostic factors and features extracted from tumor contours from CTPET has a high accuracy to predict pathologic complete response after chemoradiotherapy in locally advanced rectal cancer.
The expectation is that fear of childbirth and additional pain are important reasons for choosing analgesia, or at least influence the choice. An expected reason for not choosing analgesia is that it could be detrimental for the (unborn) child. It…
To test the hypothesis that acetaminophen is a safe and effective analgesia in neonates and to determine the optimal loading dose of intravenous Acetaminophen in neonates of different gestational age subgroups.
The aim of the study is to assess the relation of gingival abrasion to recession in both manual and power brush users. Gingival recession, exposure of the root surface due to apical migration of the gingival margin, affects a significant amount of…
The null hypothesis will be that Caphosol does not decrease the number of days of mucositis > grade 1, whereas the alternative hypothesis is that it will decrease the number of days of mucositis > grade 1 with 50%.
In this study the hypothesis will be tested that gemcitabine has a radiosensitizing effect in addition to 131I-MIBG therapy which will lead to increased anti-tumour effect in neuroblastoma.
The primary objective of the REBEL study is to collect data needed to design control policies to diminish the spread of ESBL-producing Gram negative bacteria in the Dutch population.
High-risk human papillomavirus (hr-HPV) DNA testing complementary to current cytology examination (i.e. Pap test) of cervical smears has shown an increased sensitivity and negative predictive value (NPV) for cervical cancer and its precursor lesions…
ARA290 will reduce disease activity in rheumatoid arthritis.
Stepped cased finding of women with increased fracture risk using questionnaires , bone densitometry and vertebral morfometry and treatment with bone sparing drugs of those with indcreased fracture risk in primary care reduces fractures.
It is hypothesised that the use of intra-operative ultrasonography in the excision of palpable breast cancer compared with the standard palpation-guided surgery will improve the ability to spare healthy breast tissue while maintaining or even…
Modern dressings containing silver are more effective than topical antibiotic treatment for healing of PEG-site infections.
Overweight and obesity are already prevalent in 4- till 8-year-old children. Obesity-inducing behaviours in young children have been found to track throughout the life span. Acknowledging the lack of effective interventions aimed at preschool…
The response in cerebral blood flow upon ingestion of a liquid meal differs between males and females.
Hemiarthroplasty will show quicker recovery of functional capacity of the affected upper limb in 2 years compared with open reduction and internal fixation with an angle stable locking compression plate in the treatment of dislocated three and four…
Skin temperature can possibly affect the effect of scalp cooling. First a pilot study will be conducted to check the feasibility of the main study. The primary objective of the main study is to identify a cut-off score under which alopecia can be…
An intracutaneously sutured ileostomy may be more effective than a transcutaneously sutured ileostomy to reduce peristomal dermatitis, leakage and costs and to improve quality of life of patients with an ileostomy.
Guided imagery will have positive effects on pain, self-efficacy and functional status of patients diagnosed with fibromyalgia.
1. Has tailored information on hepatitis B prevention more effect on test behaviour than generic information? 2. Does 'cultural tailored' information on hepatitis B prevention have more effect on test behaviour than tailored information?
The aim of this study is to determine the safety and efficacy of intramyocardial injection of autologous bone marrow cells in no-option patients with severe ischemic heart failure.