7356 results
Primary objectiveTo evaluate if tralokinumab after 14 weeks of treatment (at steady state) changes the metabolism of substrates of CYP 1A2, 2C9, 2C19, 2D6, or 3A4 pathways in subjects with moderate-tosevere atopic dermatitisSecondary objectivesTo…
The aim of the study is to test whether the implementation of a package of specific measures during the night shifts at the emergency room, alertness and performance during the night, sleep and physical complaints in general change.In addition, we…
The Role of microbial produced ethanol in etiology of Non-Alcoholic Steatohepatitis (ETHANASH trial)
To investigate whether microbial produced ethanol plays a role in the development of NASH.
The present study aims to address the limitations of earlier research, by employing a large sample size, and investigating the possibility that music therapy has an effect on wellbeing of people with dementia when using blinded outcome assessments…
Neurotransmitter systems, such as dopamine, are influenced by sex hormones (Riccardi et al., 2011); in fact, with respect to sex differences in dopaminergic neurotransmission, it has been suggested that in dopamine regulating genes, sexual…
The assumptions of the traumatic effects of coercive measures as described in the literature will be examined in the present study. The research questions are how coercive measures are experienced by patients, to what extent these measures are…
1. Dutch patients with Addison's disease treated with suboptimal glucocorticoid replacement therapy have a reduced QoL; 2. Prevalence of the metabolic syndrome is higher among patients with Addison's disease treated with suboptimal…
Usage of SDD or SOD has been shown to reduce the incidence of ventilator associated pneumonia (VAP) and to improve patient survival. SDD and SOD were shown not to increase resistance of bacteria colonizing the digestive tract. It can not be excluded…
Exercise training in the fasted state might be a more effective strategy to maximize glycemic control in T2DM patients, as opposed to exercise training in postprandial state.
MRD detection using next generation sequencing (NGS) on circulating tumor DNA (ctDNA) from PTLD patients using a gene panel previously used in diffuse large B-cell lymphoma (DLBCL) may be feasable
Administration of magnesiumsulphate has the potential to elicit muscle relaxation. We hypothesize administration of intramuscular magnesiumsulphate can reduce CRPS-related dystonia.
Poor sleep is a potential risk factor for impulsive and aggressive behavior. Our hypothesis is that treatment of sleeping problems in forensic psychiatric patients ameliorates sleep and general psychopathology, and reduces impulsivity and aggression…
Primary aim of the randomised trial is to elucidate the efficacy of, respectively, Oral Appliance (OA) and Continuous Positive Airway Pressure (CPAP) therapy in the management of the Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS). It is…
The primary hypothesis is that attentional bias modification (ABM) training towards and away from pictorial itch stimuli results in altered attention for pictorial itch stimuli. Secondarily, it will be explored whether attentional bias modification…
Muscle weakness in patients admitted to the Intensive Care Unit lengthens duration of mechanical ventilation, weaning and hospital stay. One of the causes for muscle weakness is critical illness polyneuromyopathy (CIPM). The incidence of CIPM varies…
Overweight and childhood obesity are still serious health problems, especially among children from families with lower socio-economic status (SES). Current obesity prevention programs are often not focussed on children’s first years of life,…
Reinforcement with prophylactic slowly-resorbable TIGR Matrix mesh in high-risk patients undergoing midline laparotomy is effective.
1. Is there, by using a vaginal tampon, less postoperative bleeding?; 2. Are there, by using a vaginal tampon, less postoperative infections?; 3. Is the result of prolapse surgery negatively influenced by not using a vaginal tampon?; 4. What kind of…
1. It is feasible to perform lymphatic mapping in locally advanced uterine cervical cancer. 2. There are lymph nodes on the lymphatic map which are not included in the radiation treatment plan or did not receive sufficient radiation dose.