809 results
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
We hypothesize that the risk of any congenital abnormality in fetuses with an early increased NT that normalizes, will be lower than those with persistent increased NT after 11 weeks of gestation.
Primary objectives: 1. Assess the feasibility of FMT in PD patients. 2. Assess the safety of FMT in PD patients. Secondary objectives: 1. Explore whether FMT leads to alterations in motor complications (fluctuations or dyskinesias) and…
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
To demonstrate superiority of left ventricular septal pacing over right ventricular pacing and to investigate the additional effect of capturing the left bundle branch in left ventricular septal pacing (LVsP). This will be done by studying…
To assess the association between secondary brain injury in intracranial haemorrhage and the involved inflammatory response. We want to correlate perihematomal inflammation, serum inflammation markers, increased blood-brain-barrier leakage and…
To identify characteristics of comorbid insomnia in patients with OSA as a factor for predicting CPAP compliance. To answer this, the aim can be divided into three parts with corresponding research questions. Part 1: Identification of COMISA…
To assess the potential of AT1R and ETAR antibodies to serve as a biomarkers for clinical deterioration in COVID-19.
The objective of this study is to assess the safety and feasibility of WATS for esophageal sampling after nCRT in patient with esophageal cancer.
The project aims to improve mental health and wellbeing in the workplace by developing, implementing and evaluating an intervention targeting both clinical (depressive, anxiety disorders) and non-clinical (stress, burnout, depressive symptoms)…
to test the feasibility of the study protocol for operability, intensity and logistics and to test whether the chosen activities can be measured as expected, in order to provide a guideline for testing maximum aerobic capacity and the metabolic…
To test the first feasibility and safety of intratumoral 166-holmium microspheres implantation in pancreatic cancer in a controlled, open-surgery setting.
Objective: To investigate the feasibility and acceptability of the online cognitive behavioral therapy program (eHealth CF-CGT), so that the program can be tailored to the needs of the patient
To assess cognitive impairment in participants with highly-active RMS, having participated in the CLARIFY MS trial, at 4 years afterinitial dose of cladribine tabletsTo assess health related quality of life (HRQoL) in participants with highly-…
The primary objective of this study is to analyse the feasibility and internal validity of Magtrace in the sentinel node procedure in breast cancer in the Breast Care Centre in Zuyderland Medical Centre; with the ultimate goal to make the sentinel…
1. Implementation of a point-of-care fully automated analysis of neutrophils in the emergency department trauma bay in monotrauma geriatric hip fracture patients. 2. To determine if patients who develop infectious complications demonstrate decreased…
The primary objective is to measure the dose of cerebral ischemia, as a measure of cerebral hypoperfusion, before, during and after aortic arch surgery. Secondary objectives include parameters that influence the occurrence of cerebral ischemia (…
Our objective is to study SARS-CoV-2 transmission of a- and pre-symptomatic carriers during a mass gathering event with social distancing and hygiene public health measures.Secundary objectives:- To estimate the prevalence of a- and pre-symptomatic…
Primary Objective: To investigate the efficacy and safety of octreotide treatment (a somatostatin analogue) in decreasing the transfusion requirements (IV iron infusions and / or red blood cell transfusions) in patients with GI bleeding caused by…
The main objective of this study is to perform a quality assessment on several new techniques, used in the laboratory of Translational Cancer Genomics and Proteomics