756 results
Vapor ablation can effectively and safely eradicate short BE segments
We hypothesize that the inter-observer variability of the CPR, MCA, UA and UtA measurement will be less than intra-observer variability due to normal biological variation of cardiovascular control.
The aim of this study is to investigate the effect of two distalisation techniques of a gastric bypass in revisional surgery with standardised limb lengths in total weight loss (TWL) and the need for treatment for protein calorie malnutrition (PCM…
The project proposed here aims to leverage recent advancements in fMRI methodology and lucid dreaming induction strategies to investigate brain networks and connectivity during REM sleep and its associated lucid vs. non-lucid dream experiences.
This study aims to phenotype and endotype bronchiectasis during stable disease and exacerbations, to develop strategies for personalised medicine.3.1 Primary ObjectiveTo determine molecular endotypes of bronchiectasis which can guide response to…
The two main objectives are: A) identify patterns of psychofysiological stress in staff and clients prior to challenging behaviour, and B) explore possibilities of biofeedback on the psychofysiological stress level of staff, and whether biofeedback…
Our main objective is to develop and validate body fluid biomarkers that detect CAA in Alzheimer*s Disease patients during life.
To assess accuracy of 18F-sodiumfluoride (NaF) positron emission tomography (PET) and serum non-oxidized parathyroid hormone (PTH) as an accurate, reliable and easy applicable diagnostic tools for the assessment of bone turnover in chronic kidney…
To study the effects of in vitro culture conditions, such as different culture media or oxygen tension, on omic layers (i.e. genome, epigenome and transcriptome) of preimplantation human embryos and to relate this to chromosoom instability (CIN).
Determining the robustness of [18F]-FDG PET/CT based quantitative features in metastatic melanoma patients by test-retesting [18F]-FDG PET/CT scans and varying post processing scan settings, for future diagnostic and prognostic clinical application.
The primary objective is to determine the safety, tolerability and preliminary efficacy of repeated intrathecal administration of NurOwn® (MSC-NTF: Autologous Mesenchymal Stem Cells [MSC] Secreting Neurotrophic Factors [NTF]) given three times at…
To determine if stimulated salivation during the biodistribution of PSMA-ligands causes a significant increase in the accumulation in salivary glands
Our primary objective is:i. To assess the quantity and regional distribution of [18F]DPA-714 binding as a marker of microglial activation in patients with FTD compared to controls. Our secondary objectives are: i. To compare the quantity and…
1) to study the effects of 4 weeks of HIIT compared to 4 weeks of CAE on motor and non-motor aspects of PD; 2) to investigate the association between blood biomarkers for neuroplasticity / neurodegeneration and motor and non-motor performance for…
To assess the accuracy of the screw placements after using a surgical guide in patients operated for intra-articular tibial fractures.
In this explorative study, we aim to:• Analyze neoantigens expressed on different tumors of CMMR-D patients, to identify possible target antigens for DC vaccination studies.• Investigate the presence of pre-existing immune responses against…
Part 1Primary- To characterise the wheal response over time following skin challenge with ascending concentrations of SP on a single daySecondary- To characterise the wheal response over time following skin challenge with ascending concentrations of…
Primary objective: 1. To establish whether obtaining CTCs of mHSPC patients by DLA for single cell genotyping and phenotyping warrants further clinical exploration. Secondary objectives: 1. To investigate the number of CTCs in peripheral blood of…
In this study we aim to evaluate whether the levels of TRAIL and/or IP-10, alone or in combination, are a sign of viral infection at a stage before symptoms arise. We will assess the diagnostic value of the biomarkers alone and/or in combination,…
To investigate the prevalence of transthyretin amyloid cardiomyopathy in HFpEF patients with a cardiac implantable electronic device (CIED) such as a pacemaker or Implantable Cardioverter Defibrillator (ICD)