28 results
Overall aim of the study is to investigate which decision-making models for patient participation are used in practice in end-of-life decision-making and how appropriate are these models for different patient groups.Secondary Objective(s): 1. In…
1. To assess reference values of a pre-defined set of biomarkers for AKI in *surgical* infants with normal kidney function.2. To determine the incidence of AKI in critically ill infants, according to pRIFLE criteria.3. To evaluate the sensitivity…
Primary objective: to compare glucose profiles collected by CGM on days with and without haemodialysis in a group of insulin treated diabetic patients who are on regular hemodialysis treatment. Secondary objectives: o assessment of frequency and…
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
Primary:- to evaluate the pharmacokinetics, in particular the routes and extent of metabolism and excretion, of the study medication after a single oral dose of 1 mg 14C-labeled study medicationSecondary: -to identify the metabolic profile of the…
Primary objective:- To determine the clinical efficacy of multiple doses of 177Lu-DOTA-cG250 at MTD in patients with advanced renal cancer using RECIST criteriaSecondary objectives:- To determine the toxicity of the treatment as defined by NCI…
Measuring the effects of light therapy during hemodialysis on objective en subjective sleep parameters, sleepiness during dialysis, mood and melatonin rhythm. De results of this pilot study can be used to design a larger study on light therapy in…
The aim of the study is to observe whether microcirculatory perfusion follows the decrease in preload caused by hemodialysis in a population with an intact and a disturbed microcirculatory autoregulation.
To investigate the Ertapenem plasmaconcentration time curves in a dosingscheme of three administrations per week after hemodialysis in patients with end stage renal disease depending on hemodialysis. To find a pharmacokinetic model to describe…
The purpose of this trial is to demonstrate the superior efficacy of pudendal neuromodulation in treating patients with neurogenic overactive bladder, who have failed conservative treatment, in a randomized cross-over trial.Symptoms of urinary…
This study is a phase I trial. Primary objective is to evaluate the safety of combined radiotherapy with Panitumumab in bladder preservation in invasive bladder cancer. Secondary objectives are to investigate the efficacy of combined radiotherapy…
To investigate the incidence of CIN in three hospitals where patients are treatedaccording to the current guidelines, to identify the prediction risk factors and toobtain blood and urine samples that will allow future identification and evaluation…
The aim of the study is to evaluate the safety of the Flex catheter and the effect of the renal denervation on blood pressure.
Objective:Primary aim of the study is estimating the diagnostic accuracy of translabial 3D ultrasonography of thepelvic floor as compared to MR imaging, the reference standard, for diagnosing levator defects inwomen with POP. Our secondary aim is…
The primary objectives are the following:- To assess the safety profile and determine the Optimal Biological Dose (OBD) or Maximum Tolerated Dose (MTD), whichever occurs first, of intravesically administered TMX-101. The secondary objectives are the…
To dermine whether the endothelial glycocalyx is damaged by ATG therapy.
The objective of the proposed pilot study is to explore acceptability and feasibility of structured and adequate symptomatic treatment in adult women with uncomplicated UTI.
What is the most reliable way, defined as the lowest percentage rate of urines which are contaminated, to collect urine in pregnant women to asses bacteriuria? Comparison of three different methods of collection: midstream morning urine, midstream…
Primary: To investigate if there is a correlation between findings of transabdominal ultrasound measurement of the rectum and rectal digital examination. Secondary: To investigate if there is a correlation between an enlarged rectum (diameter &…
1. Monitoring of cellular (T-cel) specifc immune response in bladder and bloodsamples after intravesical BCG- therapy. 2. Monitoring and comparing T-cell responses after BCG therapy in patients with clinical BCG-related complications to the T-…