974 results
1. To establish whether serial exhaled breath analysis using eNose can detect invasive pulmonary aspergillosis in patients with prolonged chemotherapy induced neutropenia (neutrophil counts <0.5 x 10^9 for more than 7 days).2. To establish…
The goal of the planned studies is to determine the significance of afferent and efferent motor processes in facial expressions that may impact evaluative judgments or responses induced by linguistic and pictorial representations of facial…
To investigate whether children with OI who use a wheelchair (for long distances) can reliably perform a valid shuttle ride test in order to assess the levels of health-related fitness in this group.
1. Measurement of the 24-hour glycemic profile in response to acute submaximal hypoxic and hyperoxic exercise in order to determine its effectiveness and select the most efficient method in reducing post-exercise hyperglycemia prevalence in…
- to evaluate (cost-) effectiveness of a personalized health intervention among workers of 40 years and older with high physical work demands to contribute to a reduction in CVD and sustainable employability.
Primary:* To determine if alisertib improves overall response rate (ORR; complete response [CR] plus partial response [PR]) versus a selection of single agents in patients with relapsed or refractory peripheral T-cell lymphoma (PTCL)* To determine…
In this trial will be investigated if a new formulation of valacyclovir, e.g. oral solution, is bioequivalent to valacyclovir tablets. This comparison will be made by determining pharmacokinetic parameters (AUC0-*, Cmax, and tmax) of both…
The main objective of this study is to develop a method to identify susceptible pathways of redox metabolism and bioenergetics in peripheral blood cells and induced pluripotent stem cells from patients with PD and DLB.
We wish to study the absolute numbers, ratio and phenotype of CD27+IgE+ and CD27-IgE+ memory-B-cells in blood of atopic children who suffer from proven IgE-mediated asthma/hay fever, atopic dermatitis or food allergy and compare these with healthy…
To demonstrate that combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.
The objectives are to evaluate the degree of bilateral benefit gained from having a second implant with respect to speech perception, spatial hearing, and listening effort.
The objective of the current experiment is to validate cognitive- and EEG-diagnostic markers of ADHD-symptoms by studying differences in cognitive task performance between subjects diagnosed ADHD, undiagnosed ADHD subjects showing ADHD symptoms and…
ObjectiveThe main goal of this investigation is to evaluate the thyroid hormone response in patients with TMNG and control subjects in response to various pharmacological and physiological stimuli, administered according to the dynamic exposure test…
The objective of the present project is to demonstrate that the cerebellum supports both the ability to implicitly learn motor sequences and the ability to implicitly learn language sequences and its dysfunction will be detrimental to both skills.…
Primary Objective: * To determine the effects of pharmacogenetic screening for CYP2D6 on the time to reach adequate serum drug levels according to the guidelines.Secondary Objective(s): * To determine the effects of pharmacogenetic screening for…
Research if the incidence and types of wound infections are comparable in the sterile versus clean wound treatment.
The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…
Main objectiveTo investigate whether the sympathetic stimulation of BAT, as assessed with a MIBG SPECT-CT scan, differs between lean and obese individuals.Secondary Objectives: To investigate whether the slope of the correlation between sympathetic…
The main objective is to compare the rate of clinical pregnancy at approximately 5-8 weeks gestational age for the Day 3 embryo transfers that used Eeva predictions with morphology grading to that for Day 3 embryo transfers using morphology grading…
Primary Objective: To determine the height and duration of viremia, the seroconversion rate and the level of neutralising antibodies in relation to - the actual number of CD4 positive cells- the nadir of CD4 positive cells- the duration of CD4 count…