806 results
This research will explore how fast phonemic restoration of degraded speech can be learned. This will be done by training and testing normal-hearing listeners in several sessions with interrupted speech. We will also train a group of normal-hearing…
To investigate both the clinical and economical(-healthcare evaluation) improvement of BVR using best responder criteria in patients with severe COPD.
To assess microglial activation in first episode patients with psychotic symptoms and first episode medication naïve patients with psychotic symptoms compared to healthy controls using the positron emission tomography (PET) tracer [11C]-R-PK11195.
To demonstrate that extended postoperative antibiotic treatment does not decrease the infectious complication rate in laparoscopic cholecystectomy for acute cholecystitis.
Primary Objective:Proof of concept study designed to document the safety and feasibility of adjuvant treatment with the PICSO Impulse system in patients with acute anterior ST-segment elevation myocardial infarction (STEMI) treated with primary PCI…
The goal of this pragmatic, randomized controlled study is to determine the effectiveness of two relaxation techniques, eg. TM or HT added to the treatment of paediatric primary headaches in comparison to standard medical treatment (SMT). TM or HT…
The first line of research encompasses the frequency, severity, and (dis)similarities of perceptual and attentional impairments in near and far space. Differential impairments of near and far space processing are more likely to be found when spatial…
To determine if HF subjects whose treatment is assisted by a daily BNP measurement that is integrated into a home health management system will have improved clinical outcomes versus subjects whose treatment includes home health management but is…
The purpose of this clinical trial is to demonstrate the safety and efficacy of the Z-Lig* device for the treatment of ruptured ACL of the knee compared to allograft.
Primary Objective: The main objective of this study is to demonstrate that PVC suppression therapy on top of conventional heart failure treatment improves cardiac systolic function as assessed by quantitative echocardiography in patients with…
The main goal of this study is to recruit and obtain magnetic resonance images in a large sample of bipolar patients and controls from the Netherlands, in order to find brain abnormalities specific for bipolar disorder. We will also perform genetic…
Primary: progression-free survival in the GSK1120212-group in comparison with the docetaxel group. Secondary: safety and tolerability, response rate, duration of response, overall survival, PK.
The main aim of the present study is to improve our understanding of the role of blood-brain barrier function and cerebral perfusion in dementia of the Alzheimer*s type.
The objective of the study is to evaluate the safety and efficacy of eculizumab to prevent AMR in sensitized recipients of living donor kidney transplants requiring desensitization therapy.
The primary study objectives are: (1) to determine whether an internet-based guided self-help intervention is effective in reducing symptoms of depression in glioma patients; (2) to determine the impact of the intervention on the HRQOL of both…
Optimization of the supplementation of vitamins and minerals1. In patients who received a gastric banding for treatment for their morbid obesitya. Reduction of iron deficiencyb. Reduction of Vitamin B12 deficiencyc. Reduced Vitamin D deficiency2. In…
To ascertain whether the survival time distribution for patients randomized to the investigational arm is consistent with longer survival as compared to patients randomized to the control arm.
Primary objective of the OPTICARE study is to evaluate whether patients with acute coronary syndrome (ACS) will derive additional benefit from an extended CR program compared to standard CR.
To evaluate the efficacy, safety, tolerability, and pharmacokinetics of bevacizumab when added to postoperative radiotherapy with concomitant and adjuvant temozolomide (TMZ) and to determine whether the addition of anti-angiogenic therapy with…
The purpose of this study is to evaluate whether thyroid hormone replacement therapy in type 2 diabetic patients suffering from overt hypothyroidism will improve muscular mitochondrial function, lower ectopic fat accumulation in muscle and liver,…