365 results
To compare the efficacy of maintenance therapy with an equal monthly dose of imiglucerase when administered at a frequency of once every four weeks versus once every one or two weeks, in adult type I Gaucher disease patients in stable and good…
Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…
It is hypothesized that long term disabled persons who participate in the MDR program will return to work and have less mental and/or physical limitations to prevent te pre-disability income. Furthermore an explorative study into the process…
Our hypothesis is that peroperative fluid restriction will lead to a significant reduction of solid phase gastric emptying time ¨C measured by radionuclide scintigraphy-, and a reduction in its related postoperative complications.
A more gradual training program for novice runners, will result in a reduction of running related injuries in novice runners.
The primary aim of the study is: 1. To assess the role of an early intensification of two "AML" induction blocks versus protocol Ib directly after induction, in a randomized way in MR and HR patients. Secondary aims are: 2. To assess the…
The collaborative care approach is expected to be more effective and more cost-effective compared to care as usual.
The aim of the study is: 1. To investigate the benefits and risks of hormonal substitution after prophylactic adnectomy in women with an increased risk for breast- and/or ovarian cancer due to a genetic predisposition; 2. To compare the effects and…
The promotion of safe sports participation proves effective in a physical education setting, resulting in a reduction of lower extremity injuries in children.
The on-line intervention will prove to be significantly more effective in improving mood and reducing diabetes-related distress in diabetes patients with minor to moderately severe depression compared to the control condition (CAU, supplementend…
Our hypothesis is that rebound thrombin generation occurs in ICU-patients after abrupt cessation of heparin treatment in terms of elevation of coagulation-markers and reduction fibrinolysis-markers; IV-weaning of heparin reduces this rebound…
To determine the effect on HbA1c of a disease-specific enteral formula compared to an isocaloric standard enteral formula (control) in type 2 diabetic patients after 12 weeks of supplementation.
A health education program for both patients and general practitioners will change behaviour by 15%.
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Correction of sub-clinical prolongation of coagulation tests (i.e., PTT between 14.7 – 20 seconds and platelets < 100 x 109/L) and transfusion of platelets in patients with Ascal®, significantly decreases the incidence of clinical significant…
A randomized controlled trial of geriatric liaison intervention in frail surgical oncology patients.
The primary objective of this study is to show that early detection of geriatric patients at risk of preventable functional decline following a surgical procedure under general anesthesia for a solid tumor, combined with a geriatric liaison…
The go4it programme will improve bmi, glucose tolerance and life style.
Bipolar devices will minimize the disadvantages of the monopolar device; risk of electrolyte disturbances by using saline irrigation, bleeding and the risk of nervous stimulation
Local corticosteroid injections combined with usual care will have a positive effect on experienced recovery and will reduce pain at 3 and 12 months follow up compared to usual care alone.