340 results
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
This project focuses on detection of predisposing factors (e.g. instability of the joints) for the onset of early CMC-1 joint osteoarthritis based on CMC-1 joint kinematics. For this purpose we need to develop a new diagnostic 4D imaging tool. The…
The aim of this study is to explore the incidence of MTX related gastro-intestinal in a large cohort of JIA patients. Secondly, we want to investigate the effect of psychological behavioural therapy or switch to parenteral MTX dosing to ameliorate…
Objective of the study is to verify whether the movement pattern after anterior cervical discectomy normalises, in case of implantation of a cervical disc prosthesis.
The primary objective of this study is to determine (differences in) patient satisfaction with pain relief and pain intensity (Numeric Rating Scale) using a step 1 vs. a step 2 based analgesic regimen.The secondary objective is to determine…
To optimize the management of non-chronic shoulder pain in primary care by the introduction of ultrasound as a diagnostic triage tool. The following research questions will be addressed:1. What are the effects of diagnostic ultrasound and its…
The main hypothesis is that circulating inflammatory mediators are the main causative factor for the emergence of generalized osteoporosis in patients with Rheumatoid Arthritis (RA). 1.Does the serum of patients with active RA, containing…
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
To investigate the (cost) effectiveness of early ACL reconstruction (<6 weeks after injury), compared to the usual timing of ACL reconstruction (> 3 months after injury). Hypotheis is that early ACL reconstruction results in less loss…
The follow-up study has two main research questions:o Is the treatment of early RA according to the COBRA-light schedule as effective (based on DAS44 score, ACR/EULAR remission criteria, HAQ score and the Sharp/van der Heijde score) as standard…
Part one: To quantify the influence of weightbearing on the IMA, HVA and DMAA, measured according the actual gold standard of measurement.Part two: Validation of the Dutch version of the Foot Ankle Outcome Score (FAOS) and the Dutch version of the…
Compare hemi-arthroplasty with reverse arthroplasty in the treatment for displaced three- or four-part proximal humerus fractures
The first aim of the present study is to examine whether the pain experience in adults with Down syndrome (without dementia) differs from the pain experience in adults without intellectual disability, after correction for mentale age, comorbidity…
Primary Objective: Compare grip strength of working patients with OAH with healthy workers.Secondary Objective(s): To compare the results of the supplementary tests of working patients with OAH with healthy workers.To describe the possible…
Primary ObjectiveDifference in incidence of an avulsion injury and morphological changes of the levator ani muscle after a first normal vaginal delivery between participants with and without a mediolateral episiotomy.Secondary ObjectiveChanges in…
Optimizing the amount of ropivacain and gabapentin, used for local infiltration (LIA) during TKA procedures by measuring the outcomes of pain (by using the 100 mm Visual Analogue Scale (VAS)), adverse effects, length of hospital stay, cumulative…
Is DEXA accurate to predict bone loss of the femur before undergoing hip revision arthroplasty and provide a tool for quantification of bone loss of the femur before hip revision arthroplasty? Can DEXA be used to monitor bone remodelling after hip…
Obtain more insight in the preferred macronutrient composition of an oral nutritional supplement.
1. To compare cartilage changes after KJD and after HTO, based on MRI, radiographs and biomarkers, evaluated 2 years post treatment. 2. To compare clinical efficacy after KJD and after HTO during 2 year follow-up by a questionnaire (KOOS; for pain,…
Primary Objective: Our main goal is to contribute to the identification of an attentional profile of the paediatric TBI population, by analysing the quality and efficiency of alerting, orienting, executive and sustained attentional functioning. This…