303 results
Acetaminophen is effective in treating self-reported sleep problems, in particular insomnia.
We hypothesize that addition of low-dose haloperidol prophylaxis (1.0mg twice-daily) on top of the existing standard of care reduces in-hospital delirium incidence, severity and duration in a general patient population, age 70 years or over, who are…
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
1. To investigate the efficacy of Cogmed working memory training in reducing behavioral symptoms in children with neuropsychiatric disorders and borderline intellectual functioning; 2. To investigate whether WM training improves neurocognitive…
The primary objective of this study is to test the hypothesis that risperidone given orally in a dose of 0.25 – 3.0 mg/d depending on body weight (eq. to approximately 0.01 – 0.04 mg/kg/d) for 12 weeks is superior to placebo in reducing…
1. Volume intervention by a diuretic and moderate sodium diet potentiates the antiproteinuric effects of aliskiren in patients with residual albuminuria during conventional RAAS-blockade; 2. Aliskiren neutralizes the reactive rise in plasma renin…
Determine safety and kinetics of IQNLF in humans.
Administration of MPH during brain development, but not in adulthood, results in an altered outgrowth of the dopaminergic system. This long-lasting disturbance of the dopaminergic system may result in behavioral abnormalities, such as anxiety and…
To evaluate if Epigallocatechin gallate (EGCG) is an effective treatment for pain in endometriosis patients by using Visual Analogue Scores (VAS).
No formal hypothesis is set in this study. The sample size is based on feasibility considerations.
Oxytocin administration leads to stronger empathic reponses and faster emotional processing.
1. Assessment of safety of seasonal and pandemic inactivated whole virion influenza vaccines; 2. Assessment of immunogenicity of the whole virion vaccines; 3. Comparison of the safety profile of the whole virion vaccines with a split virion vaccine.
Intravenously administered rhAPC has protective effects on HDM-LPS induced allergic lung inflammation.
The primary objectives are:- To evaluate clinical remission for the 2 subcutaneous (SC) maintenance regimens of ustekinumab in subjects with moderately to severely active Crohn*s disease induced into clinical response with ustekinumab in the…
To study the effect of a nerve block of the infrapatellar nerve with local infiltration with lidocaine or saline on chronic anterior knee pain after tibial nailing.Secondairy objectives:- to measure knee pain on a VAS for eight different activities…
Aim of the studyTo study the effectiveness and toxicity of dexamethasone to prevent the occurrence of a pain flare after short schedule radiotherapy for painful bone metastases and to define the optimal schedule of dosing.Research questions:1. What…
Primary Objective: - To confirm the effect of dexamethasone on clinical outcome in patients admitted with CAP.Secondary Objectives: - To study what patients admitted with CAP benefit most from dexamethasone therapy. Predefined subgroup analysis…
Subjects randomized to the placebo treatment are unlikely to benefit from the study. However, OAB is not a life-threatening disease and it is not expected that a 12 to 15 week exposure to placebo treatment will have a negative impact on disease…
Primary ObjectiveTo investigate the possible efficacy of combined administration of 0.5 mg sublingual testosterone and 10 mg tadalafil in increasing sexual satisfaction during sexual activity in the domestic setting in healthy female subjects with…