2 results
Approved WMOCompleted
Objectives: For patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) enrolled in this study, the objectives are as follows:Primary: -To assess the efficacy of bardoxolone methyl relative to placebo.Secondary…
Approved WMOCompleted
To evaluate the safety and tolerability of ascending multiple PO doses of AMG 986 in heart failure patients (Part C).* To characterize AMG 986 pharmacokinetics (PK) after IV infusion and oral administrationin heart failure patients.* To characterize…