3 results
Approved WMORecruiting
The objective of this project is to study the role of dopaminergic mechanisms in apathy, mood and HDD in patients with PD. What is the involvement of the dopaminergic neurotransmitter system in motivation and reward processes in PD and the clinical…
Approved WMOWill not start
Determine the influence of methylphenidate treatment on sleep-wake rhythm and endogenous melatonin rhythm.
Approved WMOCompleted
The objectives of this study are to establish whether methylphenidate PD effects can be measured using neurocognitive tasks, to describe the drug concentrations of methylphenidate in saliva, to describe the PK/PD relationship using the obtained…