4 results
Primary objectives:The primary aims of this study are to explore the relation of the extent of VS dopamine release and amphetamine-induced behavioral responses and to characterize the PD effect of repeat-dose amphetamine in healthy subjects.…
To assess the effects of dexamphetamine with and without alcohol on simulated driving performance.
Primary Objectives(1) investigate the safety and tolerability of JNJ-54175446 after multiple consecutive dose administrations;(2) investigate the plasma pharmacokinetics of JNJ-54175446 following multiple dose administration in healthy male subjects…
Primary:To evaluate the efficacy of 3 doses of RhuDex vs placebo for the treatment of PBC in patients with an inadequate response to UDCA.Secondary:• To identify efficacious RhuDex dose(s) for the treatment of PBC for further evaluation in phase III…