27 results
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
The primary aim of this study is to examine the effectiveness of a psychobiological intervention combining oxytocin administration with ERT. We hypothesize that the combined intervention will be more effective in improving emotion recognition skills…
Evaluate the efficacy of nonavalent HPV vaccination in women with a CIN lesion who will undergo or have undergone a LEEP in preventing recurrent CIN II-III after 24 months.
Our primary aims are 1) to test with observational and electrophysiological techniques whether intranasal oxytocin administration to mothers of young infants increases their defensive reactivity and protective approach responses in mildly…
To evaluate the effects of intranasal oxytocin compared to placebo administration on appetite, satiety and food intake.Also effects on social behavior, BMI, body composition, IGF-I levels and genetic differences (deletion / mUPD). To assess oxytocin…
Our primary objective is to investigate whether oxytocin administration can affect empathy and emotion recognition in healthy and antisocial adolescents. We expect that oxytocin will enhance empathy and emotion recognition in both healthy and…
In a series of randomized control trials (RCTs) the following hypothesis will be tested: Intranasal administration of oxytocin and vasopressin affect neural and behavioral responses to infant signals and threat to the infant.* Oxytocin and…
To evaluate the effects of intranasal oxytocin versus placebo on social behaviour and also on eating behaviour in children with PWS.
Objective: This study hypothesizes that an oxytocin inhalation will increase prosocial behavior and reduces social anxiety during social interaction specifically in patients with SAD in comparison to a clinical and healthy control group
- to assess the effects of intranasal administration of oxytocin in comparison to placebo on trust, as measured by the behavioural response to the Trust game- to assess the effects of intranasal administration of oxytocin in comparison to placebo on…
Our study aims at investigating whether male adults with ASD differ from healthy male adults in their neurophysiological responses to positive and negative empathy-evoking pictures when taking oxytocin intranasally once. To this end we will compare…
In this study we will assess these prosocial effects in an objective way i.e. by means of computer tasks and we will investigate the role of two potential mediators and the role of a genotype variant in the mechanism underlying prosocial behavior.…
In this study neural responses to infant crying will be measured with fMRI. In addition, the neural base of emotion understanding will be examined with fMRI. Participants will look at pictures of adults and infant and they have to infer the mental…
To study whether the administration of oxytocin leads to stronger empathic responses on 3 different empathy-related tasks compared to a placebo.
In this study we focus on behavior in response to different infant signals, including crying as well as smiling. More specifically we investigate the behavioral differences of an individual towards different infants who are either perceived as happy…
To assess the analgesic effect of ARA290 in chronic pain patients
The proposed study has two objectives. First, we will examine the neural mechanisms of aversive responding to infant cries in healthy female subjects. We will compare participants who showed high cardiovascular responses to infant cries with…
This proposal centers on hormone-behavior dynamics in paternal caregiving, with the goal of gaining a better understanding of the development of human paternal caregiving. There is limited information on the hormonal basis of caregiving patterns in…
With the proposed study we want to gain insight into the neaural mechanisms underlying (the development of) shame-proneness and fear of failure. We want to investigate whether the administration of oxytocin modulates effects of love withdrawal and…
In this study we will assess the effect of ARA290 on nerve damage by taking 4 skin bipsies during treatment.