168 results
Reduce previously learned positive associations with alcoholic drinks by administring propanolol after reactivation of the alcohol-related memory associations.
The aim of the present pilot study is to obtain insight in the attainability of a study investigating the effectiveness of NeuroCARE NFT in more than average stressed but otherwise healthy young adults, using the current design. The claims that…
- To educate adolescents on clinical drug studies by involving them as project team members and participants in an intervention trial of negligible risk and minimal burden; - To investigate the CNS effects of caffeine on neurocognitive and…
Primary objectives: Stress response: To determine whether acute alcohol consumption shortly after a psychological/mental stressor attenuates the stress response recovery.Cholinergic status: To determine whether prolonged moderate alcohol consumption…
To investigate whether the psychomotor and cognitive effects of alcohol are exacerbated by GSK1144814 in healthy subjects.
The proposed study has two objectives. First, we will examine the neural mechanisms of aversive responding to infant cries in healthy female subjects. We will compare participants who showed high cardiovascular responses to infant cries with…
To investigate the effect of AMG 785 compared to placebo on time to radiographic healing of fresh tibial diaphyseal fractures.
To evaluate the overall safety and tolerability of intrathecally administered single ascending bolus doses of Xen2174 in healthy subjectsTo evaluate the effects of Xen2174, following its administration as a single intrathecal bolus, on EEG activity…
The present study aims at testing whether a CPC-mouthrinse has a potential to inhibit *de novo* plaque formation as compared to a placebo and hexetidine.
Project 1: To investigate the neuroanatoimical correlates of attentional processing bias in nicotine addicts, using fMRI.Project 2: To examine whether attentional biases are dependent on dopaminergic transmission in the mesolimbic system using…
Primary Objective:* To investigate the effects of THC on fMRI activation patterns in healthy volunteersSecondary objective:* To assess the feasibility of pharmacokinetic/pharmacodynamic (PK/PD)-analyses for THC-induced fMRI-activation patterns* To…
To assess the effect of betahistine on the severity / intensity of motion sickness
The primary objective of this study is to assess the efficacy of duloxetine 60 mg once daily (QD) compared with placebo on the reduction of pain severity as measured by the Brief Pain Inventory (BPI) 24-hour average pain score in patients with…
The current study is designed as a first exploration of this model. The hypothesis is that haloperidol will lead to an amelioration of the *psychotomimetic* effects of the THC-challenge.
To asses the effect of opioid receptor blockade on fentnayl induced pain relief
To determine the efficacy of oral supplementation with vitamin B12 and folic acid in the prevention of fractures.
The aim of the present study is get more insight into the effects of alcohol on acute changes in brain communication en behavioral inhibition. It is hypothesized that alcohol will result cause impairments in the ability to inhibit behavioral…
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To scrutinize the role of OT in human social-emotional behaviour and gain insight in the neurobiological mechanism by which the peptide exert their effects.