4793 results
Does addition of lenalidomide to chlorambucil and rituximab result in better response rates with acceptable toxicity.
The present study aims to get more insight into the efficacy of treatment with nilotinib and the various aspects that govern optimal response, of which adherence is a primary endpoint. We hypothesize that patients who experience inadequate response…
We hypothesize that the quality of diabetes treatment, measured as glycaemic control, is worse in patients with T2DM and colorectal- and breast cancer treated with curative intent, compared to T2DM patients without cancer, at 1 and 2 years after…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
To assess the change in voiding pattern and quality of life in children who receive BoNT-A treatment in a prospective setting.
The aim of this study is to describe the last phase of life of people with young-onset dementia. The research questions for this prospective observational study are: 1. What is the practice of end of life care in people with young-onset dementia…
Main question: What is the value of the propensity for reinvestment (measured by the Movement Specific Reinvestment Scale) in predicting the functional mobility (measured with he Rivermead Mobility Index) of stroke patients after 15 weeks of…
The hyperfiltration hypothesis implies that children with a solitary functioning kidney are at risk to develop hypertension, (micro)albuminuria and chronic kidney disease. We aim to develop an individualized risk profile for children with a solitary…
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
Establish the safety and feasibility of sequential chemotherapy and SRT.
The aim of the present study is to investigate whether EMDR is an effective method to treat low self-esteem and if this is more effective than CBT. Hypothesis: 1. Participants will improve on measures of self-esteem, psychological symptoms and…
To identify whether a short axis approach (SAA) or a long axis approach (LAA) to ultrasound guided peripheral cannulation is superior when performed by ED nurses without prior ultrasound experience.